Amyotrophic lateral sclerosis: current therapeutic perspectives

V Kumar, T Kashav, MI Hassan - Pathology, prevention and therapeutics …, 2019 - Springer
… in the non-pharmacological therapy trials in ALS. Currently, no therapeutic effort seems to
be … , but recent findings in ALS will certainly help in the discovery of an effective treatment. …

Impact of traumatic brain injury on amyotrophic lateral sclerosis: from bedside to bench

CK Franz, D Joshi, EL Daley… - Journal of …, 2019 - journals.physiology.org
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative … Patients with amyotrophic
lateral sclerosis (ALS) may have a … Current treatments only have a small effect on progression, …

A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?

X Xu, D Shen, Y Gao, Q Zhou, Y Ni, H Meng… - Translational …, 2021 - Springer
treatment of spasticity in ALS patients, as they can control spasticity with safety and efficacy
in multiple sclerosis [58… cohort study has revealed high treatment satisfaction with nabiximols, …

Therapeutic approaches to amyotrophic lateral sclerosis from the lab to the clinic

VP Chavda, C Patel, D Modh, YN Ertas… - Current Drug …, 2022 - ingentaconnect.com
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease that affects adults and
… from bench to bedside in the field of ALS treatment. More than 160 drug candidates or ther…

Translational study for amyotrophic lateral sclerosis treatment

S Schröder, G Litscher, W Pan - Frontiers in Neurology, 2023 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive
loss of upper and lower motor neurons. Despite significant scientific efforts in the last …

Current status and new avenues of stem cell-based preclinical and therapeutic approaches in amyotrophic lateral sclerosis

L Mazzini, F De Marchi, L Buzanska… - … on Biological Therapy, 2024 - Taylor & Francis
… mechanisms responsible for the therapeutic action of cell therapy drugs, thus reducing the
… therefore needed to successfully transition SC-based therapy in ALS from bench to bedside. …

Advances, challenges, and perspectives in translational stem cell therapy for amyotrophic lateral sclerosis

E Abati, N Bresolin, G Comi, S Corti - Molecular Neurobiology, 2019 - Springer
… Moving stem cells research from bench to bedside requires a thorough knowledge of
their … of unproven treatments to patients outside clinical trial and drug agencies’ approval [43]. …

[HTML][HTML] From bedside to bench-in vivo and in vitro evaluation of mechanically assisted cough treatment in a patient with bulbar amyotrophic lateral sclerosis

T Andersen, O Fondenes, OD Røksund… - Respiratory Medicine …, 2022 - Elsevier
… with Amyotrophic Lateral Sclerosis, the … Amyotrophic Lateral Sclerosis experienced that
treatment with MI-E was exhausting and inefficient. Despite adjustments of settings, all treatment

Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials

SA Goutman, MG Savelieff, SA Sakowski… - … investigational drugs, 2019 - Taylor & Francis
… cell therapy for ALS holds great promise. Throughout its development from bench to bedside,
… and patients’ safety, advocating good clinical trial design to truly assess treatment efficacy. …

New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022

JS Jiang, Y Wang, M Deng - Frontiers in pharmacology, 2022 - frontiersin.org
Medical Innovation and Research, Peking University Third Hospital, Beijing, China Amyotrophic
lateral sclerosis … In the recent past, there have been just two drugs approved for treatment