[HTML][HTML] Neuroinflammation in amyotrophic lateral sclerosis and frontotemporal dementia and the interest of induced pluripotent stem cells to study immune cells …

E Liu, L Karpf, D Bohl - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
… Inflammation is a shared hallmark between amyotrophic lateral sclerosis (ALS) and …
reasons of failures linked to therapeutic trials with immunomodulator drugs. Then we present the …

TAR DNA-binding protein of 43 kDa (TDP-43) and amyotrophic lateral sclerosis (ALS): A promising therapeutic target

YA Ojaimi, A Dangoumau, H Alarcan… - … on Therapeutic …, 2022 - Taylor & Francis
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that lacks an effective
treatment. … Moreover, bench-to-bedside translation is complicated in the absence of well-…

TDP-43 and Neurodegeneration: From Bench to Bedside

V Kumar, MK Jaiswal - 2021 - books.google.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are common
neurodegenerative disorders that are relentlessly progressive, fatal, and without effective treatment, …

Preclinical research into amyotrophic lateral sclerosis: a comparison of established and novel techniques and models

S Guerra - 2021 - researchdirect.westernsydney.edu …
… Finally, I provide evidence that administration of 50mg/kg CBD as a novel treatment is not …
potential of eg novel treatments in diseases with narrow treatment windows such as ALS. …

[HTML][HTML] Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside

YY Ma, X Li, JT Yu, YJ Wang - Translational Neurodegeneration, 2024 - Springer
… ), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington’s disease
(… and treatments that can reshape the gut microbiome, serving as potential therapies for NDs (…

Molecular Chaperones' Potential against Defective Proteostasis of Amyotrophic Lateral Sclerosis

S Kinger, AR Dubey, P Kumar, YA Jagtap… - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neuronal degenerative condition identified via a …
in ALS pathogenesis presents a significant challenge in its treatment. Here, we review how the …

[HTML][HTML] Key disease mechanisms linked to amyotrophic lateral sclerosis in spinal cord motor neurons

V Bottero, JA Santiago, JP Quinn… - Frontiers in molecular …, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no modifying
treatments available. The molecular mechanisms underpinning disease pathogenesis are …

The links between diabetes mellitus and amyotrophic lateral sclerosis

R Vasta, F D'Ovidio, G Logroscino, A Chiò - Neurological Sciences, 2021 - Springer
… However, two editors’ letters pointed out the lack of adjustment of body mass index (BMI)
in the analyses, the exclusion of patients with T1DM, and the role of drug medication on the …

Amyotrophic Lateral Sclerosis

L Taggart, G Porter - Primary Care Occupational Therapy: A Quick …, 2023 - Springer
Medication interactions and the need for additional referrals and … bench Lift chair/seat
Hoyer lift Pivot transfer device Hospital bed Grab bars Handheld shower equipment Bedside

Metabolic abnormalities, dietary risk factors and nutritional management in amyotrophic lateral sclerosis

E D'Amico, G Grosso, JW Nieves, A Zanghì… - Nutrients, 2021 - mdpi.com
… only treatment [12]. In 2017, the second drug approved by the US Food and Drug Administration
(… ; however, it has not been approved by European Medicine Agency (EMA). A study on …