Evidence of genetic epistasis in autoimmune diabetes susceptibility revealed by mouse congenic sublines

R Collin, V Dugas, AN Pelletier, G Chabot-Roy… - Immunogenetics, 2021 - Springer
locus on mouse chromosome 12. Indeed, an interim linkage analysis, presented in this study,
suggested that a locus on mouse chromosomechromosome 18 (pancreatic lymph nodes). …

Deletion of Vβ3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells

C Ye, SA Clements, W Gu, AM Geurts… - Proceedings of the …, 2023 - National Acad Sciences
… We identified mouse mammary tumor provirus (Mtv)3 as underlying insulin-dependent
diabetes 32 (Idd32) diabetes resistance locus in the T1D susceptible NOD mouse, the primary …

[PDF][PDF] Basile Lebailly, Francina Langa, Christian Boitard, Philip Avner & Ute

C Rogner - academia.edu
… The Idd6 locus on distal chromosome 6 is a type 1 diabetes susceptibility locus of the
nonobese diabetic (NOD) mouse (Smink et al. 2005) that protects against spontaneous diabetes …

CD226 deletion reduces type 1 diabetes in the NOD mouse by impairing thymocyte development and peripheral T cell activation

MR Shapiro, WI Yeh, JR Longfield, J Gallagher… - Frontiers in …, 2020 - frontiersin.org
… in the non-obese diabetic (NOD) mouse would impact type 1 diabetes incidence by altering
T … , the Idd21.1 risk locus of the non-obese diabetic (NOD) mouse model of type 1 diabetes

Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase

SA Ochsner, RT Pillich, D Rawool, JS Grethe… - Iscience, 2022 - cell.com
… Investigator-generated transcriptomic datasets interrogating circulating immune cell (CIC)
gene expression in clinical type 1 diabetes (T1D) have underappreciated re-use value. Here, …

Computation of Transcriptional Networks of Circulating Immune Cells in Type 1 Diabetes

SA Ochsner, RT Pillich, N McKenna - Available at SSRN 4052017 - papers.ssrn.com
… The autoimmune condition type 1 diabetes (T1D) is a … a murine autoimmune diabetes locus
(Hook et al., 2011), and numerous DNA 368 variants associated with increase autoimmune

Fresh Ideas, Foundational Experiments: Immunology and Diabetes

MT Hubert, MS Horwitz, BT Fife - 2019 - books.google.com
mouse has been used extensively and has provided significant contributions to our mechanistic
understanding of autoimmunity and type 1 diabetes (… Idd10/18, Idd16, and Idd21 cause a …

[PDF][PDF] The role of genetic variants in the development and long-term outcome of the treatment of lumbar intervertebral disc degeneration

Á Biczó - 2023 - repo.lib.semmelweis.hu
… between cellular aging and age-related IDD by using a p16-3MR transgenic mouse model
… Mean age was 48.1 years with a range from 18-89years. The … In an in vitro mouse model …