… often associated with hemodynamic disturbances. Understanding … s pharmacokinetic model
[29] to estimate the fentanyl effect-site concentrations and Schnider’s pharmacokinetic model …

… PNA), and PNA also determines hemodynamic alterations in cardiac output and … systems
ontogeny) and models in open source platforms in order to make progress in the field of thermo…

… So, various in silico computational e-resources, databases, and simulation softwares are
being used for the determination of pharmacokinetic (PK) and pharmacodynamic (PD) …

… assume that unbound drug concentration within the tissue is in thermodynamic equilibrium
with free-drug concentration in the circulatory system. Thus, the unbound blood or plasma …

… pressure method on pharmacokinetics and … system (Diprifusor) and fentanyl was administered
at a dose of 2–3 µg/kg each time analgesia appeared to be inadequate. Hemodynamic …

… which regulatory mechanisms affecting hemodynamic and BBB characteristics are different
from uninjured brain. We hypothesized that the physiology-based PK model would therefore …

… In this chapter, we present the pharmacokinetic properties of … efferent arteriole having distinct
hemodynamic properties [30, 55]. … Using non-equilibrium thermodynamic arguments and …

… hemodynamics (heart rate, blood pressure and cardiac contractility) and cardiac pathology
45 . The integrated measurement technologies within this model … with DAPI (Thermo Fisher) …

… system and provide the neuroprotective effect, hemodynamic … Therefore, a computational
fluid dynamics (CFD) model was … a physiologically based pharmacokinetic (PBPK) model to …

Frontiers | Identification of pharmacokinetic markers for safflower injection using a combination
of system pharmacology, multicomponent pharmacokinetics, and quantitative proteomics …