Erythropoietin in the clinical trials of the cardiac disease, what is and what is not

MMM Tehrani, M Foroughi - Journal of Cellular & Molecular …, 2019 - brieflands.com
… the effects of EPO treatment in patients with MI and heart failure (… review of the cardioprotective
effects of erythropoiesis-stimulating … An updated and comprehensive meta-analysis and …

[PDF][PDF] Cardioprotective effect of erythropoietin in rats with acute myocardial infarction through JNK pathway.

GQ Li, M Chen - European Review for Medical & …, 2019 - europeanreview.org
… The present investigation explored the cardiac function indicators, the serum inflammatory
levels, and cell apoptosis, as well as the related mRNA and protein expression levels of …

[HTML][HTML] Are There Any Cardioprotective Effects or Safety Concerns of Erythropoietin in Patients With Myocardial Infarction? A Systematic Review

W Jean-Baptiste, AY Ali, B Inyang, FS Koshy, K George… - Cureus, 2022 - ncbi.nlm.nih.gov
… or protective value of EPO on the heart and safety concerns … Some studies were able to find
some cardioprotective impacts… any cardioprotective effect and safety concerns of EPO after …

[HTML][HTML] Erythropoietin administration exerted neuroprotective effects against cardiac ischemia/reperfusion injury

T Chunchai, N Apaijai, J Benjanuwattra… - Current Research in …, 2022 - Elsevier
… Furthermore, the administration of EPO resulted in cardioprotection by stimulating PI3K/Akt
and mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) in …

Erythropoietin and its derivatives: from tissue protection to immune regulation

B Peng, G Kong, C Yang, Y Ming - Cell death & disease, 2020 - nature.com
… These small peptides prevent the cardiovascular side effects of EPO and are promising as
clinical drugs. This review briefly introduces the receptors and tissue-protective effects of EPO

Role of erythropoiesis-stimulating agents in cardiovascular protection in CKD patients: reappraisal of their impact and mechanisms

T Miura, T Sato, T Yano, A Takaguri, T Miki… - Cardiovascular Drugs …, 2023 - Springer
… factors or comorbidities were resistant to the cardioprotective effects of ESAs because of …
erythropoietin receptors. In this review, we briefly discuss basic and clinical data on the impact

[HTML][HTML] Cytoprotective effects of erythropoietin: What about the lung?

L Haine, CH Yegen, D Marchant, JP Richalet… - Biomedicine & …, 2021 - Elsevier
… , we [11] and others, showed that Epo plays a key role in neuroprotection [21], cardioprotection
[22], … effects of Epo in many organs such as brain, kidney, heart or retina and proposed …

Erythropoietin-mediated cardioprotection in hearts subjected to ischemia reperfusion

DE Vélez, VEM Cordero, R Hermann… - Journal of …, 2023 - jme.bioscientifica.com
… study was to investigate the effects of EPO on the Akt/glycogen … EPO improved the functional
recovery of the heart subjected … beneficial effects exerted by acute treatment with EPO were …

Non-hematopoietic erythropoietin-derived peptides for atheroprotection and treatment of cardiovascular diseases

A Krupen'Kina Liliya - Research Results in Pharmacology, 2020 - cyberleninka.ru
… mimic the cytoprotective effects of EPO is one of the important tasks of modern pharmacology.
To date, compounds with an amino acid sequence identical to that of EPO, but differing in …

[PDF][PDF] Erythropoietin doping: cardiovascular effects in athletes

W Jelkmann - Ann Sports Med Res, 2020 - researchgate.net
effects of rhEpo and its analogs on the heart and on blood vessels, with emphasis on the
human responses. Adverse effects … When the cardioprotective effects of ARA290 were studied …