[HTML][HTML] Identification of key DNA methylation-driven genes in prostate adenocarcinoma: an integrative analysis of TCGA methylation data
N Xu, YP Wu, ZB Ke, YC Liang, H Cai, WT Su… - Journal of translational …, 2019 - Springer
… pathway analysis found five significantly enriched pathways. … Epigenetic changes and
modifications are a crucial … To confirm the candidate hub genes we obtained, two datasets (…
modifications are a crucial … To confirm the candidate hub genes we obtained, two datasets (…
[HTML][HTML] Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers
… integrative analysis strategy to identify key regulators and pathways … pathways was identified
is significantly larger than that … -evidenced genes could also perform well in other datasets, …
is significantly larger than that … -evidenced genes could also perform well in other datasets, …
[HTML][HTML] … and epigenetic alterations induced by pesticide exposure: integrated analysis of gene expression, microRNA expression, and DNA methylation datasets
… of the present study was to identify modifications in gene miRNA … much more significant if we
consider that these genes were … the identification of genes with an altered methylation status …
consider that these genes were … the identification of genes with an altered methylation status …
[HTML][HTML] Comparative analysis on abnormal methylome of differentially expressed genes and disease pathways in the immune cells of RA and SLE
Q Fang, T Li, P Chen, Y Wu, T Wang, L Mo… - Frontiers in …, 2021 - frontiersin.org
… Therefore, we collected relevant microarray data sets for B- … of identified hub genes, we
analyzed the expression of these … the methylation levels of other three genes were not significant. …
analyzed the expression of these … the methylation levels of other three genes were not significant. …
[HTML][HTML] Integrated analysis of gene expression and DNA methylation profiles in ovarian cancer
G Gong, T Lin, Y Yuan - Journal of Ovarian Research, 2020 - Springer
… downregulated genes were detected and involved in pathways … In this study, DNA methylation
datasets in ovarian cancer … component analysis showed that the genes were significantly …
datasets in ovarian cancer … component analysis showed that the genes were significantly …
[HTML][HTML] Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes
RF Pérez, P Santamarina, JR Tejedor… - Journal of translational …, 2019 - Springer
… after the normalization procedures for our generated datasets… found 110,726 CpGs whose
methylation level significantly … and robustness of the methylation changes found in this study. …
methylation level significantly … and robustness of the methylation changes found in this study. …
[HTML][HTML] Epigenome-wide meta-analysis of DNA methylation and childhood asthma
… In the smaller data sets of paired gene expression and methylation … Using Ingenuity Pathway
Analysis, we identified pathways, … functions, significantly enriched (P < .05) for the genes to …
Analysis, we identified pathways, … functions, significantly enriched (P < .05) for the genes to …
[HTML][HTML] Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis
Y Liang, C Zhang, DQ Dai - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
… genes without changing the sequences. However, studies of … colon cancer genes from TCGA
were utilized as the dataset. … ” pathway was identified as the most significantly associated …
were utilized as the dataset. … ” pathway was identified as the most significantly associated …
[HTML][HTML] Roadmap of DNA methylation in breast cancer identifies novel prognostic biomarkers
BP de Almeida, JD Apolónio, A Binnie… - BMC cancer, 2019 - Springer
… We have identified 368 DNA methylation changes that … To identify CpG sites showing
the most significant and … Using the METABRIC [31] dataset we were able to validate the …
the most significant and … Using the METABRIC [31] dataset we were able to validate the …
[HTML][HTML] Genome-wide profiling of DNA methylation and gene expression identifies candidate genes for human diabetic neuropathy
… Of the 998 DEGs, we found that 542 genes were significantly … , we determined differentially
altered molecular pathways in both … analysis of methylomic and transcriptomic datasets and …
altered molecular pathways in both … analysis of methylomic and transcriptomic datasets and …