Shared heritability of human face and brain shape

S Naqvi, Y Sleyp, H Hoskens, K Indencleef… - Nature …, 2021 - nature.com
… To more directly test for sharing of genetic effects between brain and face shape, we
intersected the 472 loci described in this study with 203 loci previously associated with face shape …

Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders

NV Radonjić, JL Hess, P Rovira, O Andreassen… - Molecular …, 2021 - nature.com
… (SMDs) in regional brain volume and cortical thickness between … brain regions for:
attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder

Common brain disorders are associated with heritable patterns of apparent aging of the brain

T Kaufmann, D van der Meer, NT Doan… - Nature …, 2019 - nature.com
… distinct patterns of apparent brain aging in several brain disorders and reveal genetic
pleiotropy between apparent brain aging in healthy individuals and common brain disorders. …

The genetic architecture of the human thalamus and its overlap with ten common brain disorders

T Elvsåshagen, A Shadrin, O Frei… - Nature …, 2021 - nature.com
… between thalamus volumes and ten neurological and psychiatric disorders. Further … of brain
disorders and the pleiotropic loci identified by our analyses could inform such experiments. …

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

B Zhao, JG Ibrahim, Y Li, T Li, Y Wang, Y Shan… - Cerebral …, 2019 - academic.oup.com
… We examined the heritability of regional brain volumes (P ~ 100) captured by single-nucleotide …
regional brain volumes are highly heritable in this study population and common genetic …

[HTML][HTML] The association between familial risk and brain abnormalities is disease specific: an ENIGMA-relatives study of schizophrenia and bipolar disorder

SM De Zwarte, RM Brouwer, I Agartz, M Alda… - Biological …, 2019 - Elsevier
… This study found differences in brain abnormalities between FDRs-SZ and FDRs-BD, in
particular, a divergent effect in ICV. This converse effect on ICV suggests that there may be …

Risk in relatives, heritability, SNP-based heritability, and genetic correlations in psychiatric disorders: a review

BML Baselmans, L Yengo, W van Rheenen… - Biological Psychiatry, 2021 - Elsevier
… Since these methods are relatively new, we estimated the SNP-based heritability of all
major psychiatric disorders using publicly available GWAS summary statistics (https://www.med.…

The reliability and heritability of cortical folds and their genetic correlations across hemispheres

F Pizzagalli, G Auzias, Q Yang, SR Mathias… - Communications …, 2020 - nature.com
… of brain structural and functional differences are important to identify as potential risk factors
for heritable brain diseases… 1 consortium, have identified common genetic variants that have …

The genetic architecture of human brainstem structures and their involvement in common brain disorders

T Elvsåshagen, S Bahrami, D van der Meer… - Nature …, 2020 - nature.com
disorders. In additional clinical data from 5062 individuals with common brain disorders and
… , bipolar disorder, multiple sclerosis, mild cognitive impairment, dementia, and Parkinson’s …

Shared vulnerability for connectome alterations across psychiatric and neurological brain disorders

…, Alzheimer's Disease Neuroimaging Initiative… - Nature human …, 2019 - nature.com
… to brain alterations across multiple brain disorders. We report on a cross-disorder connectome
study … matched controls across 8 psychiatric and 4 neurological disorders. We extracted …