PKCδ Mediates Mineralocorticoid Receptor Activation by Angiotensin II to Modulate Smooth Muscle Cell Function

Q Lu, AP Davel, AP McGraw, SP Rao… - …, 2019 - academic.oup.com
aldosterone acting via the MR regulates FKBP51 gene expression in SMCs via the same
SRE… We previously demonstrated a proatherogenic effect of aldosterone that is associated with …

Long Noncoding RNA Tug1 Promotes Angiotensin II–Induced Renal Fibrosis by Binding to Mineralocorticoid Receptor and Negatively Regulating MicroR-29b-3p

J Zhang, Y Zhang, J Gao, M Wang, X Li, Z Cui, G Fu - Hypertension, 2021 - Am Heart Assoc
… Tug1 expression in the presence or absence of angiotensin II or aldosterone measured
by real… , thereby regulating their abundance and function by preventing binding to protein-coding …

Regulation of aldosterone secretion

SM MacKenzie, JC Van Kralingen, E Davies - Vitamins and hormones, 2019 - Elsevier
… Secretion of the major mineralocorticoid aldosterone from … disruption of CYP11B2 gene
function leads to excessive … key active component of the RAS, angiotensin II (AngII). AngII exerts …

[HTML][HTML] Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex

B Caroccia, PE Vanderriele, TM Seccia… - Journal of …, 2021 - journals.lww.com
mineralocorticoid hormone [1,2] . More than a dozen factors … generated angiotensin peptides
can be functionally active in … the presence of 10 −7 mol/l angiotensin II (Ang II) (panel b) (n = …

[HTML][HTML] Molecular and epigenetic control of aldosterone synthase, CYP11B2 and 11-Hydroxylase, CYP11B1

Y Takeda, M Demura, M Kometani… - International journal of …, 2023 - mdpi.com
… role in regulating blood pressure, cardiac function, water and … We reported that an angiotensin
II infusion in rats decreased … of protein and mRNA of the mineralocorticoid receptor in the …

Regulation of aldosterone signaling by microRNAs

MB Butterworth, DA de la Rosa - Vitamins and Hormones, 2019 - Elsevier
… The mineralocorticoid hormone aldosterone is released by … identifying miRs relevant for
aldosterone function in the kidney… by angiotensin II (AngII) to feedback and alter the expression

[HTML][HTML] DNA Methylation of the Angiotensinogen Gene, AGT, and the Aldosterone Synthase Gene, CYP11B2 in Cardiovascular Diseases

Y Takeda, M Demura, T Yoneda, Y Takeda - International Journal of …, 2021 - mdpi.com
… blocker (ARB) or mineralocorticoid receptor antagonist (MRA… Aldosterone synthesis is
regulated by angiotensin II and … in APAs compared with non-functioning tumors, but no significant …

[HTML][HTML] Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis

A Lother, L Deng, M Huck, D Fürst… - Journal of …, 2019 - joe.bioscientifica.com
function of the aldosterone up- or downregulated genes, we performed molecular pathway
analysis using the gene … specific for aldosterone but augments angiotensin II and adrenergic …

[HTML][HTML] Angiotensin peptides in the regulation of adrenal cortical function

GP Rossi, L Lenzini, B Caroccia… - Exploration of …, 2021 - explorationpub.com
… , mineralocorticoid and androgen hormones. Evidence exists that angiotensin II regulates
adrenocortical function … Excess production of the main mineralocorticoid hormone aldosterone

[HTML][HTML] Aldosterone-induced microRNAs act as feedback regulators of mineralocorticoid receptor signaling in kidney epithelia.

N Ozbaki-Yagan, X Liu, AJ Bodnar, J Ho… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
Aldosterone is the final constituent of the renin-angiotensin-… By binding to the mineralocorticoid
receptor (MR) aldosterone induces the transcription of proteins that function together to …