PKCδ Mediates Mineralocorticoid Receptor Activation by Angiotensin II to Modulate Smooth Muscle Cell Function

Q Lu, AP Davel, AP McGraw, SP Rao… - …, 2019 - academic.oup.com
… of aldosterone via MR to that of cortisol via the glucocorticoid … An SRE in intron 5 of the
FKBP51 gene confers glucocorticoid … that aldosterone acting via the MR regulates FKBP51 gene

Regulation of aldosterone secretion

SM MacKenzie, JC Van Kralingen, E Davies - Vitamins and hormones, 2019 - Elsevier
… Secretion of the major mineralocorticoid aldosterone from … disruption of CYP11B2 gene
function leads to excessive … key active component of the RAS, angiotensin II (AngII). AngII exerts …

Long Noncoding RNA Tug1 Promotes Angiotensin II–Induced Renal Fibrosis by Binding to Mineralocorticoid Receptor and Negatively Regulating MicroR-29b-3p

J Zhang, Y Zhang, J Gao, M Wang, X Li, Z Cui, G Fu - Hypertension, 2021 - Am Heart Assoc
… be activated by renin-angiotensin-aldosterone system and its … miR-29b-3p and function as
a competing endogenous RNA. … sponges, thereby regulating their abundance and function by …

Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex

B Caroccia, PE Vanderriele, TM Seccia… - Journal of …, 2021 - journals.lww.com
mineralocorticoid hormone [1,2] . More than a dozen factors … generated angiotensin peptides
can be functionally active in … the presence of 10 −7 mol/l angiotensin II (Ang II) (panel b) (n = …

[HTML][HTML] Angiotensin peptides in the regulation of adrenal cortical function

GP Rossi, L Lenzini, B Caroccia… - Exploration of …, 2021 - explorationpub.com
glucocorticoid, mineralocorticoid and androgen hormones. Evidence exists that angiotensin
II regulates adrenocortical function … of the main mineralocorticoid hormone aldosterone is …

Aldosterone, the mineralocorticoid receptor, and sympathetic nervous system

EP Gomez-Sanchez, CE Gomez-Sanchez - Primer on the Autonomic …, 2023 - Elsevier
… and renal function and structure in some … Aldosterone is secreted upon synthesis in the
adrenal zona glomerulosa (ZG). Its synthesis is stimulated primarily by Angiotensin II (AII) through

Regulation of aldosterone signaling by microRNAs

MB Butterworth, DA de la Rosa - Vitamins and Hormones, 2019 - Elsevier
… The mineralocorticoid hormone aldosterone is released by … identifying miRs relevant for
aldosterone function in the kidney… by angiotensin II (AngII) to feedback and alter the expression

Molecular and epigenetic control of aldosterone synthase, CYP11B2 and 11-Hydroxylase, CYP11B1

Y Takeda, M Demura, M Kometani… - International journal of …, 2023 - mdpi.com
… role in regulating blood pressure, cardiac function, water and … We reported that an angiotensin
II infusion in rats decreased … of protein and mRNA of the mineralocorticoid receptor in the …

Endothelial cell mineralocorticoid receptors oppose VEGF-induced gene expression and angiogenesis

A Lother, L Deng, M Huck, D Fürst… - Journal of …, 2019 - joe.bioscientifica.com
function of the aldosterone up- or downregulated genes, we performed molecular pathway
analysis using the gene … specific for aldosterone but augments angiotensin II and adrenergic …

PTH modulation by aldosterone and angiotensin II is blunted in hyperaldosteronism and rescued by adrenalectomy

L Lenzini, S Prisco, PE Vanderriele… - The Journal of …, 2019 - academic.oup.com
… cells, both aldosterone (P < 0.001) and angiotensin II (P = … acting through mineralocorticoid
receptor and angiotensin type … cells express functional mineralocorticoid receptor (MR) (13), …