Aldosterone and mineralocorticoid receptor antagonists on pulmonary hypertension and right ventricular failure: a review

N Omidkhoda, F Vakilian… - Current …, 2020 - ingentaconnect.com
… not raise aldosterone, suggesting that aldosterone synthesis … The functional outcomes of
aldosterone were regulated by … (ET), angiotensin II (Ang II) and aldosterone) in the proliferation …

[图书][B] Endothelial Mineralocorticoid Receptors in Cerebrovascular and Cognitive Function in Angiotensin II-Hypertension

JM Díaz-Otero - 2019 - search.proquest.com
… actions of aldosterone in all cell types in the arteries. … and these are regulated by
mineralocorticoid receptor activation ...… TRPV4 and IKCa/SKCa mRNA expression in AngII-hypertension …

Mineralocorticoid dysfunction during critical illness: a review of the evidence

GD Nethathe, J Cohen, J Lipman, R Anderson… - …, 2020 - pubs.asahq.org
… -talk exists between angiotensin II and aldosterone, which … angiotensin I and angiotensin II
receptors, mineralocorticoid … local or tissue axes that regulate renal function, blood pressure, …

Identifying new cellular mechanisms of mineralocorticoid receptor activation in the heart

MJ Young, M Kanki, PJ Fuller, J Yang - Journal of Human Hypertension, 2021 - nature.com
… by angiotensin II as a result of renovascular hypertension. Whereas elevated aldosterone
MR as key to the regulation of pathways involved in cardiac function, as well as dysfunction, …

The mineralocorticoid receptor and the heart

CE Gomez-Sanchez, EP Gomez-Sanchez - Endocrinology, 2021 - academic.oup.com
regulation of the renin-angiotensin system. It activates the … GR and MR interaction at the
transcriptional and functionalaldosterone are the same or different depending on the gene, …

[PDF][PDF] … Actions of the Angiotensin II Receptor Blockers and Mineralocorticoid Receptor Antagonists Therapy on the Renin Angiotensin Aldosterone System Produce a …

CA Paterno Marchioli - Cardiology & Vascular Research, 2023 - scivisionpub.com
… System in hypertensive patients with normal kidney function could obtain … Angiotensin II
and Aldosterone, because some of the cellular effects of Angiotensin II occur through aldosterone

Genetics of hypertension and the renin—angiotensinaldosterone system

PC White - Molecular endocrinology, 2020 - taylorfrancis.com
mineralocorticoid receptors were specific for aldosterone, … specificity for aldosterone upon
the mineralocorticoid receptor (… enzyme's function in protecting the nuclear mineralocorticoid

Mineralocorticoid Receptors in Vascular Smooth Muscle: Blood Pressure and Beyond

ND Camarda, J Ibarrola, LA Biwer, IZ Jaffe - Hypertension, 2024 - Am Heart Assoc
aldosterone, by functioning in the nucleus as a transcription factor to … Upon aldosterone
activation of mineralocorticoid receptors in SMCs, MR induces expression of the angiotensin II

Mechanisms of mineralocorticoid receptor-associated hypertension in diabetes mellitus: the role of O-GlcNAc modification

R Jo, H Shibata, I Kurihara, K Yokota… - Hypertension …, 2023 - nature.com
… Although MR activity is mainly regulated by aldosterone, in … drugs, ie, angiotensin receptor
blockers (ARBs) or angiotensin-… in the absence of increased plasma aldosterone levels [8]. …

Mineralocorticoid receptors in the pathogenesis of insulin resistance and related disorders: from basic studies to clinical disease

G Jia, W Lockette, JR Sowers - … of Physiology-Regulatory …, 2021 - journals.physiology.org
Aldosterone is a steroid hormone that regulates blood pressure and cardiovascular function
by acting on renal and vascular mineralocorticoid … excessive angiotensin II signaling through