Mineralocorticoid receptors, neuroinflammation and hypertensive encephalopathy
ME Brocca, L Pietranera, ER De Kloet… - Cellular and Molecular …, 2019 - Springer
… function, because it binds and responds to glucocorticoids rather than to the natural
mineralocorticoid aldosterone. … salt appetite, since an additional angiotensin II antagonist is …
mineralocorticoid aldosterone. … salt appetite, since an additional angiotensin II antagonist is …
Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human …
KE Helfenberger, AF Castillo, PG Mele, A Fiore… - The Journal of Steroid …, 2019 - Elsevier
… of angiotensin II (Ang II) in protein subcellular compartmentalization, mitochondrial dynamics
and the involvement of this process in the regulation of aldosterone … has a functional role in …
and the involvement of this process in the regulation of aldosterone … has a functional role in …
Aldosterone and mineralocorticoid receptor signaling as determinants of cardiovascular and renal injury: from Hans Selye to the present
M Epstein - American journal of nephrology, 2021 - karger.com
… function. In contrast, many recent studies have demonstrated a wider and expanded role
for … the effect of angiotensin II on plasminogen activator inhibitor-1 expression, stimulating …
for … the effect of angiotensin II on plasminogen activator inhibitor-1 expression, stimulating …
The Mineralocorticoid Receptors in diabetic kidney disease
G Jia, G Lastra, BP Bostick… - American Journal …, 2024 - journals.physiology.org
… focused on targeting angiotensin II, emerging data support that 46 the mineralocorticoid
receptor (… antagonism to maximally reduce Ang II as well as aldosterone escape. Initial MR 162 …
receptor (… antagonism to maximally reduce Ang II as well as aldosterone escape. Initial MR 162 …
Pathophysiological mechanisms of mineralocorticoid receptor-dependent cardiovascular and chronic kidney disease
A Nishiyama - Hypertension Research, 2019 - nature.com
… angiotensin II induces aldosterone release from the adrenal gland, treatment with an RAS
inhibitor should reduce plasma aldosterone … of coronary endothelial function via reduction in …
inhibitor should reduce plasma aldosterone … of coronary endothelial function via reduction in …
Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice
RH Oakley, D Cruz-Topete, BO He, JF Foley… - Science …, 2019 - science.org
… and compared the gene expression and functional profiles of … renin-angiotensin system (21),
and reduced expression of Agt … /or aldosterone control their regulation through this receptor. …
and reduced expression of Agt … /or aldosterone control their regulation through this receptor. …
[HTML][HTML] Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor
K Sun, YL Wang, CC Hou, D Shang, LJ Du… - Journal of Advanced …, 2024 - Elsevier
… and renal injury in an angiotensin II (Ang II)-induced hypertensive … Schematic illustration of
NCOR1 function in collecting duct … The renin-angiotensin-aldosterone (RAS) system takes a …
NCOR1 function in collecting duct … The renin-angiotensin-aldosterone (RAS) system takes a …
Mineralocorticoid receptor in cardiovascular diseases—Clinical trials and mechanistic insights
J Bauersachs, N López‐Andrés - British Journal of …, 2022 - Wiley Online Library
… the aldosterone/mineralocorticoid receptor system (Figure 2). … (DOCA)-salt or angiotensin
II treatments have been also … role in the regulation of endothelial function, cardiovascular …
II treatments have been also … role in the regulation of endothelial function, cardiovascular …
Transcriptional Regulation and Epigenetics in Cardiovascular Cells: Role of the Mineralocorticoid Receptor
L Deng, L Hein, A Lother - Aldosterone-Mineralocorticoid …, 2019 - books.google.com
… factors might control the cell type-specific impact of MR on gene expression and function. In
… In mouse aorta, aldosterone regulated the expression of genes related to vascular function, …
… In mouse aorta, aldosterone regulated the expression of genes related to vascular function, …
[HTML][HTML] Mineralocorticoid receptor activation in vascular insulin resistance and dysfunction
AE Igbekele, G Jia, MA Hill, JR Sowers… - International Journal of …, 2022 - mdpi.com
… , angiotensin II, and adrenocorticotropin stimulation [11,12]. Aldosterone is also produced in
adipose tissue via … Recently, a gain-of-function mutation of the MRs was found to be involved …
adipose tissue via … Recently, a gain-of-function mutation of the MRs was found to be involved …