[HTML][HTML] Angiotensin-converting enzyme inhibitors induce cough

İ Yılmaz - Turkish thoracic journal, 2019 - ncbi.nlm.nih.gov
Turkish thoracic journal, 2019ncbi.nlm.nih.gov
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as
hypertension, congestive heart failure, and myocardial infarction. Although these drugs are
well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly
chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial
and requires further study. In this review, the mechanisms that are suggested in ACE-I-
induced cough pathophysiology will be discussed in detail in light of the current literature.
Abstract
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.
ncbi.nlm.nih.gov
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