Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals

MF Akhtar, A Saleem, A Rasul, MMFA Baig… - European Journal of …, 2020 - Elsevier
… Janus-activated kinase/Signal transducer and activator of … Susceptibility of cancer cells
to anti-cancer drugs is decided … also induced apoptosis in human colon cancer cell (HT-29) …

Roles of plant‐derived bioactive compounds and related microRNAs in cancer therapy

H Zou, Y Li, X Liu, Z Wu, J Li, Z Ma - Phytotherapy Research, 2021 - Wiley Online Library
… So far, studies on the anti-cancer effects of bioactive compounds … -29 colon cancer (COAD)
cells by reducing the expression of … possibly through interleukin 6 (IL6)/signal transducer and …

[HTML][HTML] Modulation of multiple signaling pathways of the plant-derived natural products in cancer

L Sun, W Zhou, H Zhang, Q Guo, W Yang, B Li… - Frontiers in …, 2019 - frontiersin.org
… of aberrant signal transduction pathways in cancer and the … has effects on a variety of
miRNAs in different cancer cellcolon cancer cells via direct inhibition of NF-κB expression and …

[HTML][HTML] … , 3'-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and …

B Biersack - Cancer Drug Resistance, 2020 - ncbi.nlm.nih.gov
… These natural compounds are also effective modulators of … of the effects of DIM on miRNA
expression in various tumor … with distinct activity against SW480 colon cancer cells. But in …

[HTML][HTML] Cardamonin attenuates experimental colitis and associated colorectal cancer

S James, JS Aparna, A Babu, AM Paul… - Biomolecules, 2021 - mdpi.com
… Cardamonin is a naturally occurring chalcone, majorly from the Zingiberaceae family, …
through microRNA modulation, cardamonin exerts its anti-inflammatory and anti-cancer effects

Anti-cancer effects of dietary polyphenols via ROS-mediated pathway with their modulation of microRNAs

Y Yoshioka, T Ohishi, Y Nakamura, R Fukutomi… - Molecules, 2022 - mdpi.com
… These polyphenols can also influence microRNA (miR) expression. In general, they can …
increased the expression of miR-200c and decreased the viability of colorectal cancer cells. …

Targeting cancer stem cells and signalling pathways through phytochemicals: A promising approach against colorectal cancer

W Liao, L Zhang, X Chen, J Xiang, Q Zheng, N Chen… - Phytomedicine, 2023 - Elsevier
… ), the Janus kinase-signal transducer and activator of … focus on natural plant compounds
targeting colorectal CSCs. … their efficient anti-cancer activity, abundant natural sources, …

Advancements of compounds targeting Wnt and Notch signalling pathways in the treatment of inflammatory bowel disease and colon cancer

Z Pu, F Yang, L Wang, Y Diao, D Chen - Journal of Drug Targeting, 2021 - Taylor & Francis
treatment of IBD and colon cancer. The compositions and biological effects of Wnt and Notch
modulators … Recent studies have demonstrated its anti-cancer properties. In DLD-1 and HT-…

Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated …

V Shrihastini, P Muthuramalingam, S Adarshan… - Cancers, 2021 - mdpi.com
compounds also alter the biological pathways and modulate … Bioactive compounds like
tanshinones, berberine, matrine, … effect on breast cancer cells by rescuing miRNA expression [145…

[HTML][HTML] The role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects

M Yuan, G Zhang, W Bai, X Han, C Li… - … Medicine and Cellular …, 2022 - hindawi.com
… the compounds they contain with respect to their anticancer … In HCT116 human colon cancer
cells, butyrate can cause cell … in prevention of cancer via modulation of molecular pathways,…