Emerging agents that target signaling pathways to eradicate colorectal cancer stem cells

VR Silva, LS Santos, RB Dias… - Cancer …, 2021 - Wiley Online Library
… κB), Janus kinase/signal transducer and activator of transcription (… for eradicating CRC stem
cells by modulating these dysregulated … in many cruciferous vegetables with anti-cancer and …

[HTML][HTML] Bioactive Compounds of Dietary Origin and Their Influence on Colorectal Cancer as Chemoprevention

P Delgado-Gonzalez, EN Garza-Treviño… - Life, 2023 - mdpi.com
… types of cancer, including colorectal cancer, by modulating various … are involved in pro- or
anti-cancer actions [57]. Several … -tumor effect by regulating the signal transduction pathways …

[HTML][HTML] Natural products for pancreatic cancer treatment: From traditional medicine to modern drug discovery

A Kim, J Ha, J Kim, Y Cho, J Ahn, C Cheon, SH Kim… - Nutrients, 2021 - mdpi.com
… The mechanisms of anti-cancer effects were divided into four … effect on breast, lung, and
colon cancer cells [62]. This … anti-inflammatory reactions through modulation of enzymes and …

[HTML][HTML] Garcinol—a natural histone acetyltransferase inhibitor and new anti-cancer epigenetic drug

P Kopytko, K Piotrowska, J Janisiak… - International Journal of …, 2021 - mdpi.com
… also deregulate expression of miRNAs involved in tumour … Epigenetics also plays an
important role in the modulation of … , HT-29 (human colon cancer cells), gastric cancer cells, oral …

[HTML][HTML] Can natural products targeting EMT serve as the future anticancer therapeutics?

S Anwar, JA Malik, S Ahmed, VA Kameshwar, J Alanazi… - Molecules, 2022 - mdpi.com
natural compounds might have promised anti-cancer activity … in SK-OV-3 cells via modulating
miR-211 expression [86]. … -resistant colorectal cancer cells via inhibiting EMT via miRNA […

[HTML][HTML] Targeting microRNAs with thymoquinone: a new approach for cancer therapy

M Homayoonfal, Z Asemi, B Yousefi - Cellular & Molecular Biology Letters, 2021 - Springer
… as an anti-cancer agent through modulating miRNAs. … ) and P38 MAPK are signal transduction
pathways that belong to … the cell cycle at G1 phase HCT116 colon cancer cell lines by the …

[HTML][HTML] Anti-cancer activity of phytochemicals targeting hypoxia-inducible factor-1 alpha

BD Yun, SW Son, SY Choi, HJ Kuh, TJ Oh… - International Journal of …, 2021 - mdpi.com
… be upregulated via nitric oxide and signal transducer and activator of … cells [102], indicating
that curcumin modulates HIF-1α … of colorectal cancer cells [109]. Investigation of the level and …

Emerging evidence on the effects of plant-derived microRNAs in colorectal cancer: a review

WJ Zhang, YY Li, ZH Xiang, J Deng, W Li, QL Lin… - Food & Function, 2023 - pubs.rsc.org
… can be used as a potential anti-cancer agent. Moreover, the … Lactobacillus and Bifidobacterium
modulate apoptotic … the gastrointestinal tract through signal transduction from enteric …

[HTML][HTML] Natural products targeting the MAPK-signaling pathway in cancer: overview

A Shi, L Liu, S Li, B Qi - Journal of Cancer Research and Clinical …, 2024 - Springer
cancer therapeutics related to MAPK signal transduction are … in colorectal cancer cells and
increase cancer cell apoptosis, … is a natural phenolic compound with high anti-cancer activity

[HTML][HTML] Quercetin, epigallocatechin gallate, curcumin, and resveratrol: from dietary sources to human microRNA modulation

E Cione, C La Torre, R Cannataro, MC Caroleo… - Molecules, 2019 - mdpi.com
… capabilities of these compounds on microRNA modulation. … effects of resveratrol were
studied in human colon cancer in … complexes responsible for cell signal transduction and the …