Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development
… of antibiotic resistance revealed that antibiotic resistance is … allowing for the rational design
of vaccines using a process known … 82,Citation86 antibiotic-resistant determinant-focused RV, …
of vaccines using a process known … 82,Citation86 antibiotic-resistant determinant-focused RV, …
Where are we and how far is there to go in the development of an Acinetobacter vaccine?
C Ma, W Chen - Expert Review of Vaccines, 2021 - Taylor & Francis
… by multidrug-resistant Acinetobacter baumannii are becoming … without the induction of drug
resistance and have a … and approaches used in the rational vaccine design, and the current …
resistance and have a … and approaches used in the rational vaccine design, and the current …
[HTML][HTML] Confronting Tigecycline-Resistant Acinetobacter baumannii via Immunization Against Conserved Resistance Determinants
… of immunization, the antibiotic resistance determinants used … We propose an immunization
approach using TGC resistance … We developed an alternative vaccine strategy targeting an …
approach using TGC resistance … We developed an alternative vaccine strategy targeting an …
Promising targets for immunotherapeutic approaches against Acinetobacter baumannii
SB de Freitas, DD Hartwig - Microbial Pathogenesis, 2022 - Elsevier
… multi-drug resistant (MDR) when they show resistance to three … use of OMVs as targets for
the development of immunization … and design, type of antibodies generated, and immunization …
the development of immunization … and design, type of antibodies generated, and immunization …
[HTML][HTML] Designing Multi-Antigen Vaccines Against Acinetobacter baumannii Using Systemic Approaches
MJ McConnell, AJ Martín-Galiano - Frontiers in Immunology, 2021 - frontiersin.org
… Antimicrobial resistance in A. … genomes for bacterial pathogens has facilitated the rational
identification of antigens over reductionist and empirical approaches for vaccine/mAb design, a …
identification of antigens over reductionist and empirical approaches for vaccine/mAb design, a …
Acinetobacter baumannii subunit vaccines: recent progress and challenges
YT Lau, HS Tan - Critical reviews in microbiology, 2024 - Taylor & Francis
… the antibiotic resistance … design to a more targeted approach using reverse vaccinology.
This review examined many recent subunit vaccine candidates for the highly antibiotic-resistant …
This review examined many recent subunit vaccine candidates for the highly antibiotic-resistant …
In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii
E Zadeh Hosseingholi, G Zarrini… - … Drug Resistance, 2020 - liebertpub.com
… vaccine candidates. The outcome of this work will be helpful to find novel vaccine design
candidates and therapeutic targets for A. baumannii through experimental investigations. …
candidates and therapeutic targets for A. baumannii through experimental investigations. …
[HTML][HTML] A subtractive proteomics approach for the identification of immunodominant Acinetobacter baumannii vaccine candidate proteins
… baumannii were captured using IgGs obtained from patient and … Results: Using the subtractive
proteomic approach, we … baumannii clinical isolates have extensive drug resistance, and …
proteomic approach, we … baumannii clinical isolates have extensive drug resistance, and …
New putative vaccine candidates against Acinetobacter baumannii using the reverse vaccinology method
… -drug resistance Acinetobacter baumannii are increasing worldwide. Discovery of the vaccine
against this … baumannii have been designed based on two aspects; the first group includes …
against this … baumannii have been designed based on two aspects; the first group includes …
[HTML][HTML] Chimeric vaccine designs against Acinetobacter baumannii using pan genome and reverse vaccinology approaches
… Due to the upsurge in antibiotic resistance mechanisms exhibited by A. baumannii, the
current … Seven of them were found to be non-toxic and have been used in vaccine design. The …
current … Seven of them were found to be non-toxic and have been used in vaccine design. The …