… 1 randomized, placebo-controlled, observer-blinded trial to evaluate the safety and immunogenicity of inactivated Streptococcus pneumoniae whole-cell vaccine in …

CA Keech, R Morrison, P Anderson… - The Pediatric …, 2020 - journals.lww.com
… (eg, high yields, low costs, etc.), if such a vaccine can be shown to induce a strong … to
evaluate the safety, tolerability and immunogenicity of an experimental SPn whole cell vaccine

[HTML][HTML] Evaluation of the oral immunogenicity of M cell-targeted tetravalent EDIII antigen for development of plant-based edible vaccine against dengue infection

BY Kim, MY Kim - Plant Cell, Tissue and Organ Culture (PCTOC), 2019 - Springer
vaccine development. In this study, we evaluated an ‘all-in-one’ tetravalent dengue vaccine
… ELISPOT, showing the mean number of antibody-secreting cells from triplicate cultures; WT …

[图书][B] Evaluation of Human T and B Cell Immune Responses to Enteric Vaccines in Human Nasopharynx-Associated Lymphoid Tissues

MA Leon-Rios - 2022 - search.proquest.com
… was shown after a three-dose oral immunization with α-GalCer-… or effector antibody-secreting
plasma cells, respectively (37-… focus on the evaluation of immunogenicity of enteric vaccines…

Progress and challenges in the clinical evaluation of immune responses to respiratory mucosal vaccines

X Zhang, J Zhang, S Chen, Q He, Y Bai… - Expert Review of …, 2024 - Taylor & Francis
… titer is a commonly used indicator for evaluating vaccine immunogenicity [Citation56]. In …
immunogenicity. Compared to homologous boosting with an intramuscularly inactivated vaccine

… cholerae O139 in humans following O139 cholera and following vaccination with a commercial bivalent oral cholera vaccine, and evaluation of conjugate vaccines …

M Kamruzzaman, M Kelly, RC Charles, JB Harris… - Msphere, 2021 - Am Soc Microbiol
… total mass of saccharide used in vaccination, we also assessed immunogenicity following
… We assessed immunogenicity in mouse serum collected from vaccinated mice, assessing …

[HTML][HTML] Adjuvants enhance the induction of germinal center and antibody secreting cells in spleen and their persistence in bone marrow of neonatal mice

AA Aradottir Pind, M Dubik, S Thorsdottir… - Frontiers in …, 2019 - frontiersin.org
immunogenicity of pneumococcal conjugate vaccine is highly age dependent and plain
pneumococcal polysaccharide (PPS) is only immunogenic … Any product that may be evaluated in …

[HTML][HTML] Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines

CJH Davitt, S Longet, A Albutti, V Aversa… - Mucosal …, 2019 - Elsevier
… We further demonstrate the mucosal immunogenicity of a … to implement an effective oral
vaccination strategy.9 Mucosal … study, we evaluated the potential of the oral delivery technology, …

[HTML][HTML] Safety and immunogenicity of the oral, inactivated, enterotoxigenic Escherichia coli vaccine ETVAX in Bangladeshi children and infants: a double-blind …

F Qadri, M Akhtar, TR Bhuiyan… - The Lancet Infectious …, 2020 - thelancet.com
Evaluation of the safety and immunogenicity of the oral inactivated multivalent … optimal for
assessing circulating antibody-secreting cell or ALS responses after oral vaccination, with only …

Oral vaccines for enterotoxigenic Escherichia coli

N Carlin, AM Svennerholm - Mucosal Vaccines, 2020 - Elsevier
antibody-secreting cell (ASC) response locally in the stomach and intestine, as tested in gastric
and duodenal biopsies from vaccinated … the safety and immunogenicity of ETVAX in large …

[HTML][HTML] Oral vaccines: A better future of immunization

KWY Kwong, Y Xin, NCY Lai, JCC Sung, KC Wu… - Vaccines, 2023 - mdpi.com
… This review introduces certified oral vaccines for adenovirus, … pylori) have been shown
to elicit significant immunogenicity … T cells facilitate B cells to differentiate into antibody-secreting