A lactococcus lactis-vectored oral vaccine induces protective immunity of mice against enterotoxigenic escherichia coli lethal challenge
J Song, L Zhao, M Song - Immunology Letters, 2020 - Elsevier
… and the quantity of antibody-secreting cells of immune organs [4]. … Evaluation of the safety
and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine …
and immunogenicity of the oral inactivated multivalent enterotoxigenic Escherichia coli vaccine …
Evaluating single-domain antibodies as carriers for targeted vaccine delivery to the small intestinal epithelium
S Bakshi, RS Garcia, H Van der Weken… - Journal of controlled …, 2020 - Elsevier
… , we evaluated the presence of mouse Fc IgG 2a -specific antibody secreting cells in different
… The subunit vaccines very often trigger only a weak immunogenic response upon oral …
… The subunit vaccines very often trigger only a weak immunogenic response upon oral …
[HTML][HTML] A systems biology approach identifies B cell maturation antigen (BCMA) as a biomarker reflecting oral vaccine induced IgA antibody responses in humans
L Mottram, A Lundgren, AM Svennerholm… - Frontiers in …, 2021 - frontiersin.org
… in oral vaccine trials is to quantify IgA antibody secreting cell (… overall immunogenicity or
adjuvanticity of the whole cell vaccine … evaluation of safety and immunogenicity of an oral ETEC …
adjuvanticity of the whole cell vaccine … evaluation of safety and immunogenicity of an oral ETEC …
The impact of product and process related critical quality attributes on immunogenicity and adverse immunological effects of biotherapeutics
Y Wen, V Jawa - Journal of pharmaceutical sciences, 2021 - Elsevier
… responses, including immunogenicity, hypersensitivity … (QbD), which requires risk assessment
and establishment of … scores based on safety, immunogenicity, pharmacokinetics (PK) and …
and establishment of … scores based on safety, immunogenicity, pharmacokinetics (PK) and …
[HTML][HTML] U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge
LM Coria, FL Martinez, LA Bruno, KA Pasquevich… - Vaccine, 2020 - Elsevier
… In this work, we evaluated the immunogenicity and protective efficacy of an … trigger a local
inflammatory response that stimulate antibody secreting B cells present in the inductive sites of …
inflammatory response that stimulate antibody secreting B cells present in the inductive sites of …
Recent strategies driving oral biologic administration
BS Alotaibi, M Buabeid, NA Ibrahim… - Expert Review of …, 2021 - Taylor & Francis
… This feature is helpful for oral vaccination as it affects immunogenicity. Many studies have
reported vaccine delivery by targeting the intestine, but the oral cavity and stomach offer a …
reported vaccine delivery by targeting the intestine, but the oral cavity and stomach offer a …
Safety and immunogenicity of a killed bivalent (O1 and O139) whole-cell oral cholera vaccine in adults and children in Vellore, South India
V Raghava Mohan, S Raj, MS Dhingra… - Plos one, 2019 - journals.plos.org
… evaluate the safety and immunogenicity … vaccine-specific antibody-secreting cell responses
are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral …
are detected at the mucosal surface of Bangladeshi subjects after immunization with an oral …
Complementary role of CD4+ T cells in response to pneumococcal polysaccharide vaccines in humans
V Jha, EN Janoff - Vaccines, 2019 - mdpi.com
… In this review, we consider the mechanisms by which … a functional association with the
immunogenicity of the vaccine. … produce PPS-specific antibody-secreting cells in the presence of …
immunogenicity of the vaccine. … produce PPS-specific antibody-secreting cells in the presence of …
Efficient mucosal immunization by mucoadhesive and ph-sensitive polymeric vaccine delivery system
L Xing, TJ Zhou, YT Fan, Y He, T Pang, KH Cho… - Macromolecular …, 2019 - Springer
… In this review, we discuss natural polymer- and synthetic … , B cells are transformed into
antibody-secreting plasma cells, … property to improve the immunogenicity of intranasal antigen …
antibody-secreting plasma cells, … property to improve the immunogenicity of intranasal antigen …
[HTML][HTML] Oral inactivated whole cell vaccine for mucosal immunization: ETVAX case study
RI Walker, AL Bourgeois - Frontiers in immunology, 2023 - frontiersin.org
… as well as IgA antibody-secreting cell (ASC) responses against … loss of immunogenicity by
reducing the dose of vaccine, even … evaluation of safety and immunogenicity of an oral ETEC …
reducing the dose of vaccine, even … evaluation of safety and immunogenicity of an oral ETEC …