… immunity because they secrete antibodies. Surviving for … follicles to establish as extrafollicular
PB, somewhat akin to T-… Recently, we showed that cMyb controls essentially all of the …

… plasma cell generation during the GC reaction is regulated … of antibodies produced by the
extrafollicular plasma cells are … B-cell fate decision toward memory B cells or plasma cells by …

… , antigen-specific plasma cells in the spleen, along with a reduction in long-term, antigen-…
We conclude that B cell response fates are critically regulated by the innate, inflammatory …

… are activated and then either immediately differentiate into ASC by extrafollicular (EF) …
antigen-BCR recognition strength and antigen valency can regulate the choice between GC …

… Extrafollicular plasma cells are short-lived and most of antibodies produced are composed
of the … However, the precise mechanism by which DNA methylation regulates plasma cell …

… I argue that the extrafollicular responses of B cells are the … of plasma cells with features
of B-1-derived plasma cells (B-… and blood is critically regulated by signaling through the …

… as a sensor of T cell help and defines high-affinity germinal center (GC) plasma cell (PC) …
Studies where IgG1 was expressed in naive B cells showed that antigen-experienced IgG1…

… Cells that fail to bind antigen and obtain T cell help will die, facilitating a Darwinian selection
process called affinity maturation. Cells that survive make a choice between … extrafollicular …

… -secreting plasma cells (PCs) and GC-derived memory B cells (… The choice between the
three lineages is, at least in part, … at least in part, regulated by the strength of BCR signaling and …

… Here, we review current understanding of how B cell … long-lived plasma cells, germinal center
cells, and memory cells; and … how B cells travel throughout the body surveying for antigen, …