… among subsets of B lymphocytes and plasma cells. … SOCE in regulating IL-10 production
by B cells and their plasmablast or … of extrafollicular plasma cells that produce antigen-binding …

… of GC B cells into plasma cells. Because plasma cells secrete antibodies that are soluble
copies of the BCR, the ongoing SHM and selection of GC B cells expressing high-affinity BCRs …

… wave of rapidly secreted antibodies from extrafollicular (EF) … B-1 cells through BCR-mediated
self-antigen recognition. In … of genes known to regulate plasma cells, such as Blimp1 and …

… to favor EF versus GC fate decision, and we found enhanced … IgG3 isotype, and a broader
antigen recognition profile (11). The … Hyperactivation of mTOR promotes rapid plasma cell …

… and non-transcriptionally regulated metabolic pathways. We … in mice showing that
antigen-specific plasma cell numbers in the … mostly localized to the extrafollicular regions of …

… Here, we show that miR-155 regulates the early expansion … a B-cell–intrinsic manner, by
tracking antigen-specific B cells in … B cells in vivo at critical stages of the extrafollicular response. …

… Upon activation B-cells then up-regulate chemo-attractant … B-cells can develop directly as
an extra-follicular (EF) … affinity, or proliferated significantly compared to plasma cells produced …

… cell clones with high affinity for pathogen or vaccine antigens … suggesting that the choice
between ASC differentiation and … to direct cell cycle reentry versus cell cycle exit for plasma cell …

… with self-antigen is a common feature of populations of naive B cells specific for foreign
Ags and a moderate level of cross-reactivity primes individual cells for optimal proliferative …

… among GC B cells to determine the outcome of affinity maturation, and regulate GC output of
memory and plasma cells to shape … -presenting cells in an antigen recognition- and contact-…