Identification of dual-function bovine lactoferrin peptides released using simulated gastrointestinal digestion

M Tu, S Xu, Z Xu, S Cheng, D Wu, H Liu, M Du - Food Bioscience, 2021 - Elsevier
… The LF hydrolysate produced using pepsin digestion showed antihypertensive (Ruiz-Giménez …
Therefore, the LFH may be able to exert an antihypertensive effect by inhibiting the ACE …

Molecular binding mechanism and identification of novel anti-hypertensive and anti-inflammatory bioactive peptides from camel milk protein hydrolysates

P Mudgil, B Baby, YY Ngoh, H Kamal, R Vijayan… - Lwt, 2019 - Elsevier
… slightly light bands of lactoferrin and serum albumin were also detected. Following enzymatic
… Digestion of bovine α-S 2 and κ-casein with pepsin released ACE inhibitory peptides with …

Bioactive Peptides and Their Presence in Some Milk Species

B Palabıçak, M Akın, M Akın, A Çelikel - Harran Üniversitesi Mühendislik … - dergipark.org.tr
… of milk in the gastrointestinal tract or hydrolysis by proteolytic enzymes (pepsin, trypsin and …
antihypertensive and antioxidative effects. Most studies have used cow milk protein to identify

Novel ACE inhibitory peptides derived from whey protein hydrolysates: Identification and molecular docking analysis

X Li, C Feng, H Hong, Y Zhang, Z Luo, Q Wang, Y Luo… - Food Bioscience, 2022 - Elsevier
hydrolysate could be a suitable resource for obtaining novelnovel ACE inhibitors for
hypertension management. … For those peptides that cannot be hydrolyzed by pepsin, trypsin, and …

[HTML][HTML] Lactoferrin Isolation and Hydrolysis from Red Deer (Cervus elaphus) Milk and the Antibacterial Activity of Deer Lactoferrin and Its Hydrolysates

Y Wang, AEDA Bekhit, SL Mason, JD Morton - Foods, 2020 - mdpi.com
Cow lactoferrin (Lf) has 708 amino acids with molecular … A great number of antimicrobial
peptides have been identified within … Both deer and cow Lf were susceptible to pepsin and were …

Identification and availability of peptides from lactoferrin in the gastrointestinal tract of mice

F Fan, P Shi, H Chen, M Tu, Z Wang, W Lu, M Du - Food & function, 2019 - pubs.rsc.org
… , 96 and 2 novel peptides were identified in the contents of … of lactoferrin cleaved by several
proteases such as pepsin, … that the pepsin hydrolysates of lactoferrin comprised fraction …

Purification and identification of xanthine oxidase inhibitory peptides from enzymatic hydrolysate of α-lactalbumin and bovine colostrum casein

YF Gao, MQ Liu, ZH Li, HL Zhang, JQ Hao… - Food Research …, 2023 - Elsevier
… and bovine colostrum casein were hydrolyzed by alkaline protease, pepsin, pancreatin, and
pepsin-… was selected based on the hydrolytic degree and hydrolysates’ XO inhibitory action. …

Production of bioactive peptides from bovine whey proteins

M Santos-Hernández, T Kleekayai… - … Traditional Applications in …, 2023 - Elsevier
… that a correlation between in vivo antihypertensive effects and an in vitro measured ACE …
enzymatic hydrolysis of bovine whey protein with pepsin and pancreatin and were identified as …

Bioactive peptides of whey: Obtaining, activity, mechanism of action, and further applications

LB Olvera-Rosales, AE Cruz-Guerrero… - Critical Reviews in …, 2023 - Taylor & Francis
… out in hypertensive patients have highlighted the effect of the … Bovine lactoferrin is part of
the innate immune system and … from the hydrolysis of α-LA and β-LG with pepsin, trypsin, …

Production and characterization of anti‐hypertensive and anti‐diabetic peptides from fermented sheep milk with anti‐inflammatory activity: in vitro and molecular …

R Pipaliya, B Basaiawmoit, AA Sakure… - Journal of the …, 2024 - Wiley Online Library
… -I properties of tryptic hydrolysates of bovine, caprine, and … mass spectra for peptide sequence
identification. The peptide … sheep whey hydrolysate treated with a novel proteinase from …