Oxidative stress and inflammation are two common risk factors in the pathogenesis of various life-threatening diseases. In recent years, antioxidant-rich medicinal plants have been extensively researched for their potential role in disease treatment and prevention. Garcinia cowa (Family Guttiferae) has been used as traditional medicine in many countries around the world. It contains numerous chemicals with various bioactivities, including anticancer, antidiabetic, and antihyperlipidemic. These effects are thought to be related to the radical scavenging effect, due to their antioxidant activities, along with other possible mechanisms such as anti-inflammatory properties. Therefore, the present review provides in-depth knowledge about the antioxidant potential of Garcinia cowa. This review provides evidence in the literature for the Garcinia cowa, from 2000 to 2022. Three bibliographic databases were used as primary sources of information (PubMed, ScienceDirect, and Google Scholar). The keywords in this research were" Antioxidant",“Asam Kandis”, and" Garcinia cowa". A total of 10 studies were included in this review according to the required criteria. Garcinia cowa has powerful antioxidant characteristics, to remove free radicals. It is clear that Garcinia cowa, with different plant parts and diverse concentrations, can have varied antioxidant capacities.