… Isodon rubescens (named “Dong-Ling-Cao” in China), a Chinese traditional medicinal herb
… cent development of oridonin derivatives which are applied as anticancer, antibacterial, anti-…

… Oridonin, one of the main active compounds isolated from Chinese herb medicine … considerable
attention for its potential antibacterial, anti-inflammatory, and antitumor applications [[2], […

… anticancer activity against a variety of tumor cells. Several structural modifications on the
oridonin and biological evaluation of its derivatives … oridonin derivatives as potential anticancer …

… anti-bacterial/inflammatory therapy for a long time in China and Asia, its major active component,
oridonin… that p53 plays a key mechanistic role in mediating oridonin's anti-cancer effect. …

… , oridonin may be a logical botanical for future researches of tumor adjuvant therapy. Figure
2 gives the antitumor mechanism of oridonin. … on these new derivatives have tremendously …

… convert into the precursor oridonin in vivo to exert antitumor activity, thereby assuming the
role of a prodrug. HAO472 was reported to bundle the antitumor efficacy of oridonin (data not …

… main active components of Rabdosia rubescens. Modern pharmacological studies have
shown that oridonin has anti-tumor, anti-bacterial, … Oridonin derivative caused apoptosis in liver …

… Antitumor and antibacterial derivatives of oridonin: a main composition of dong-ling-cao.
Molecules (Basel, Switzerland), 21(5), 575. http://dx.doi.org/10.3390/molecules21050575. …

… Notably, oridonin-derived aziridine 11 was recently identified as potential anticancer drug
… Trans-cinnamic acid derivative 12 was also recently identified as a potent cytotoxin in a …

… rubescens (also named dong ling cao) leaves (Figure 1A), … There is mounting evidence
that Ori exhibits potent antitumor … The derivative of Ori show great potential properties as an …