… aphidicolin (APH), an inhibitor of DNA polymerase to inhibit … is the endonuclease or
exonuclease activity of MRE11 that is … e MUS81 depletion inhibits mitotic DNA synthesis in …

… model DNA substrate lacking a 5′ biotin but treated as in (E… photoproducts similarly inhibit
TREX1 nucleolytic activity. We … has 3′ exonuclease activity that is inhibited by the presence …

… Aurora B activity, we treated cells with an Aurora B inhibitor, … dose of topoisomerase II inhibitor,
ICRF-193 (Figure 2d,e). Low-… of ICRF-193, but not to cytotoxic agents such as aphidicolin, …

… that POLθ binds to chromatin during DNA replication (Figure 1B). Recombinant POLθ-FL was
also able to bind replicating chromatin (Figure S1E)… DNA polymerase inhibitor aphidicolin (…

… My research on DNA polymerase started with E. coli … T7 DNA polymerase, its strong 3′-5′
exonuclease activity had … into DNA (DNA strand synthesis) were inhibited by aphidicolin (a …

… The exonuclease activity of DNA repair protein Mre11 … With the mild inhibition of DNA
replication by aphidicolin and … by the endo-nucleolytic incision of DNA that is internal to a …

… with some key differences: 1) they lack a 3’-5’ exonuclease … stalling are aphidicolin (APH),
an inhibitor of replicative DNA … Cyclin E induction, and treatment with the Wee1 inhibitor MK-…

… it in E. coli [23]. Because of their aphidicolin-sensitive phenotypes, it was anticipated that a
… Even some DNA molecules can develop structures that inhibit the elongation of the primer. …

… pools by inhibiting ribonucleotide reductase [7–9], aphidicolin, … vitro reconstituted DNA
replication studies showing that the E. … This model also predicts that 5’–3’ nucleolytic resection is …

… , E). In order to illustrate the effect of TIM loss specifically in … Ph-IAA and aphidicolin, an
inhibitor of DNA polymerases that … , an inhibitor of MRE11 which is an exonuclease responsible …