[HTML][HTML] Protective role of apigenin against Aβ 25–35 toxicity via inhibition of mitochondrial cytochrome c release

F Nikbakht, Y Khadem, S Haghani… - Basic and Clinical …, 2019 - ncbi.nlm.nih.gov
Apigenin is a potent antioxidant, anti-inflammatory, and anti-carcinogenic agent. Also, some
… the neuroprotective effects of apigenin in Aβ 25–35-induced neurotoxicity and memory …

Insights Into the Role of Copper in Neurodegenerative Diseases and the Therapeutic Potential of Natural Compounds

G Zhong, X Wang, J Li, Z Xie, Q Wu… - Current …, 2024 - ingentaconnect.com
Apigenin antagonized copper-mediatedneurotoxicity in APPsw cells and exerted … that
curcumin attenuated copper-induced neurotoxicity in SH-SY5Y cells by inhibiting mitochondrial

[HTML][HTML] Studies on apigenin and its biological and pharmacological activity in brain disorders

V Kumar, S Kundu - Advanced Pharmaceutical Bulletin, 2022 - ncbi.nlm.nih.gov
… -inflammatory properties by attenuating the expression of COX-… degeneration via reversal
of mitochondrial dysfunction. … in a copper-mediated β-amyloid neurotoxicity cell model of AD. …

Vitegnoside mitigates neuronal injury, mitochondrial apoptosis, and inflammation in an Alzheimer's disease cell model via the p38 MAPK/JNK pathway

Q Wang, H Jiang, L Wang, H Yi, Z Li… - Journal of Alzheimer's …, 2019 - content.iospress.com
… Therefore, inhibition of Aβ-mediated neurotoxicity induced by … considerable potential
anti-oxidant effects through their free … through attenuating p38 MAPK/JNK signaling during the …

[HTML][HTML] … medicinal plants as neuroprotective and therapeutic properties against amyloid-β-related toxicity, and glutamate-induced excitotoxicity in human neural cells

D Lobine, N Sadeer, S Jugreet… - Current …, 2021 - ncbi.nlm.nih.gov
… , parkin translocate to depolarized mitochondria via a PINK1-… able to prevent or disrupt β
amyloid aggregation and also … has the ability to attenuate oxidative stress and neurotoxicity (for …

Therapeutic applications of apigenin and its derivatives: micro and nano aspects

H Javid, S Ahmadi, E Mohamadian - Micro Nano Bio Aspects, 2023 - mnba-journal.com
Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation,
mitochondrion protection and MAPK signal inactivation in an AD cell model. Brain Research. …

Apigenin attenuates acrylonitrile-induced neuro-inflammation in rats: Involved of inactivation of the TLR4/NF-κB signaling pathway

F Zhao, Y Dang, R Zhang, G Jing, W Liang… - International …, 2019 - Elsevier
… potential antioxidants against neurotoxicity induced by ACN. … ], attenuating copper-mediated
β-amyloid neurotoxicity in an … is activated via the release of Cyt-c from mitochondria into the …

Flavonoids and polyphenolic compounds as potential talented agents for the treatment of Alzheimer's disease and their antioxidant activities

R Akter, MAR Chowdhury… - Current pharmaceutical …, 2021 - ingentaconnect.com
… has been effectively attenuated by Lu (20-100 μM) not only … ) prevents copper-mediated
toxicity in β-amyloid precursor … Apigenin protects HT22 murine hippocampal neuronal cells …

[HTML][HTML] Pharmacological and molecular insight on the cardioprotective role of apigenin

SD Thomas, NK Jha, SK Jha, B Sadek, S Ojha - Nutrients, 2023 - mdpi.com
Apigenin attenuated brain damage and improved neuronal … I/R injury through the mitochondrial
pathway mediated by Notch1/… and improved antioxidant activity through the regulation of …

Apigenin alleviates neuroinflammation in a mouse model of Parkinson's disease

GF Yarim, F Kazak, M Yarim, M Sozmen… - International Journal …, 2022 - Taylor & Francis
Apigenin administration attenuated MPTP-induced … with copper-mediated beta-amyloid
neurotoxic action, apigenin exerts a neuroprotective effect by maintaining mitochondrial function, …