Genome-wide association studies

E Uffelmann, QQ Huang, NS Munung… - Nature Reviews …, 2021 - nature.com
single-nucleotide polymorphisms (SNPs) and individuals, detection of population strata in
the sample and calculation of principle components. Figure depicts clustering of individuals …

[PDF][PDF] Development of single nucleotide polymorphism (SNP) markers in tropical crops

Y Dwiningsih, M Rahmaningsih… - Advance Sustainable …, 2020 - researchgate.net
… -assisted selection and genome-wide association in tropical crops are … Single nucleotide
polymorphism (SNP) marker is becoming the most popular molecular marker for those studies. …

Comparing single‐SNP, multi‐SNP, and haplotype‐based approaches in association studies for major traits in barley

A Abed, F Belzile - The Plant Genome, 2019 - Wiley Online Library
… Additionally, an individual single nucleotide polymorphism (… detected by the single-single
nucleotide polymorphism (SNP), … reported by previous genome-wide association study (GWAS…

Strong correlation between the case fatality rate of COVID-19 and the rs6598045 single nucleotide polymorphism (SNP) of the interferon-induced transmembrane …

YC Kim, BH Jeong - Genes, 2020 - mdpi.com
… the rs6598045 single nucleotide polymorphism (… polymorphism is presumed to confer
susceptibility to COVID-19 [9]. A recent genome-wide association study (GWAS) reported that two

RAINBOW: Haplotype-based genome-wide association study using a novel SNP-set method

K Hamazaki, H Iwata - PLoS computational biology, 2020 - journals.plos.org
… rare variants is one of the problems in conventional genome-wide association studies (GWAS). …
Several single nucleotide polymorphism (SNP) set approaches have been proposed to …

Polygenic risk scores that predict common diseases using millions of single nucleotide polymorphisms: is more, better?

A Cecile, JW Janssens, MJ Joyner - Clinical chemistry, 2019 - academic.oup.com
… In recent studies, this increased risk is … in genome-wide association studies (GWAS). These
SNPs are replicated across studies and more likely implicated, directly or by association, in …

Examination of the associations between m6A-associated single-nucleotide polymorphisms and blood pressure

XB Mo, SF Lei, YH Zhang, H Zhang - Hypertension Research, 2019 - nature.com
study was to investigate the association between m 6 A-associated single-nucleotide
polymorphisms … (BP) in large-scale genome-wide association studies and to test whether m 6 A-…

Estimation of a significance threshold for genome-wide association studies

AS Kaler, LC Purcell - BMC genomics, 2019 - Springer
… and genome-wide association studies (GWAS) are the two most … technologies, single
nucleotide polymorphisms (SNPs) provide … Association mapping has several advantages over the …

BLINK: a package for the next level of genome-wide association studies with both individuals and markers in the millions

M Huang, X Liu, Y Zhou, RM Summers, Z Zhang - Gigascience, 2019 - academic.oup.com
… the available Single Nucleotide Polymorphism (SNPs) with the restriction that every two QTNs
were … Fitting two PCs and their products had much worse control of P value inflation due to …

Identification of novel loci associated with hip shape: a meta‐analysis of genomewide association studies

DA Baird, DS Evans, FK Kamanu… - … mineral research, 2019 - academic.oup.com
… We aimed to report the first genomewide association study (… to be related to the risk of both
hip osteoarthritis and hip fracture. … outcomes) singlenucleotide polymorphisms (SNPs) were …