Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis

AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition …
dysfunction, contribute to the pathogenesis of atherosclerosis. This overview is focusing on the …

Inflammation in atherosclerosis—no longer a theory

P Libby - Clinical chemistry, 2021 - academic.oup.com
… plaques by pathologists such as Herbert Stary (39) received experimental support from
observations in mouse atherosclerosis that mononuclear … The pathogenesis of atherosclerosis I …

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

M Bäck, A Yurdagul Jr, I Tabas, K Öörni… - Nature Reviews …, 2019 - nature.com
… that infiltrate the developing atherosclerotic lesions also include … not found in the developing
atherosclerotic lesions 15 . … event in the pathogenesis of atherosclerosis given that oxidative …

NADPH oxidases and their role in atherosclerosis

AV Poznyak, AV Grechko, VA Orekhova, V Khotina… - Biomedicines, 2020 - mdpi.com
… In particular, the role of NADPH oxidases in atherosclerosis … regard to atherosclerosis, several
important pathological … of NADPH oxidases in atherosclerosis pathogenesis, the available …

The effects of oxidative stress on the development of atherosclerosis

M Khosravi, A Poursaleh, G Ghasempour… - Biological …, 2019 - degruyter.com
… Therefore, it can be said, that pathological agents including changes in … in the atherosclerosis
pathogenesis, especially in vascular endothelial dysfunction. In general, atherosclerosis

Potential role of protein kinase C in the pathophysiology of diabetes-associated atherosclerosis

CF Lien, SJ Chen, MC Tsai, CS Lin - Frontiers in pharmacology, 2021 - frontiersin.org
… are linked to the pathogenesis of atherosclerosis in diabetes. PKC deletion or treatment
with PKC inhibitors has been studied in the regulation of atherosclerotic plaque formation and …

The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
… in the pathogenesis of atherosclerosis [31]. XO expression is significantly higher in plaques
from symptomatic atherosclerosis … yet are also important pathological molecules in disease …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
atherosclerosis. As such endothelial cells remain quiescent throughout adult life, but under
various physiological and pathological … in the atherosclerotic pathogenesis is present; and by …

Inflammation as a therapeutic target in atherosclerosis

MT Nguyen, S Fernando, N Schwarz, JTM Tan… - Journal of clinical …, 2019 - mdpi.com
… coronary artery disease (CAD), the underlying pathology in the majority of cardiovascular …
been hypothesised to be involved in the pathogenesis of atherosclerosis [91]. Therefore, not all …

Targeting inflammation in atherosclerosis—from experimental insights to the clinic

O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
atherosclerosis. Indeed, clinical studies have now demonstrated unequivocally that modulation
of inflammation can forestall the clinical complications of atherosclerosisatherosclerosis, …