Higher levels of anti-phosphorylcholine autoantibodies in early rheumatoid arthritis indicate lower risk of incident cardiovascular events

S Ajeganova, MLE Andersson, J Frostegård… - Arthritis Research & …, 2021 - Springer
… We hypothesized that the association between IgM anti-PC and the risk of CV outcome is
different in the presence of CV risk factors. We therefore further performed analyses within the …

… against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome

EC Knudsen, I Seljeflot, TA Aksnes, J Eritsland… - Plos one, 2019 - journals.plos.org
… and coronary occlusion is the leading underlying cause of myocardial infarction and sudden
cardiacAutoantibodies directed towards a variety of oxidation-specific epitopes or self—…

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… could be related to the complexity of the LDL-oxidation process where antigens exposed
could vary to some extent, and there may also be differences in methods used for antibody

Immunoglobulin A antibodies against phosphorylcholine in rheumatoid arthritis patients and its association with clinical outcomes

A Syed - 2021 - diva-portal.org
… with the clinical outcomes. Potential immunomodulatory … antibody to target the root
causes of the inflammation and treat patients with early RA, thereby atherosclerosis and CVD

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

SK Samal, AR Qureshi, M Rahman… - Clinical & …, 2020 - academic.oup.com
… We also divided patients into inflamed C-reactive protein (CRP) > 5·6 mg/ml and non-inflamed
CRP. Antibody levels were determined by in-house enzyme-linked immunosorbent assay. …

Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death in …

IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

D Thiagarajan, N Oparina, S Lundström, R Zubarev… - Scientific reports, 2020 - nature.com
… The antibody levels were used for cases vs controls and cross-disease analysis. Statistical …
for each antibody. The correlation between antibody level and cardiovascular score (CV) was …

Non-linear relationship between anti-apolipoprotein A-1 IgGs and cardiovascular outcomes in patients with acute coronary syndromes

N Vuilleumier, S Pagano, C Combescure… - Journal of clinical …, 2019 - mdpi.com
… Because experimental evidence indicates that these autoantibodies could per se promote …
fact that we did not assess other auto-antibodies of potential CV relevance, which is outside of …

Phospholipid related antigens and protective mechanisms: Implications for cardiovascular diseases, human autoimmunity and inflammation

D Thiagarajan - 2019 - search.proquest.com
… are associated with negative cardiovascular outcomes. As a … the antibody circulating levels
and outcomes patients with CVD … The protective role of antibodies against phosphorylcholine

[PDF][PDF] Immunoglobulin G1 antibodies against phosphorylcholine are associated with protection in systemic lupus erythematosus and atherosclerosis: Potential …

D Thiagarajan, R Fiskesund, A Frostegård… - ACR open …, 2020 - Wiley Online Library
phosphocholine (POVPC); the antibody binding is tested for all known antigens that expose
PC. Capsular polysaccharide (C-PS), POVPC conjugated with bovine serum albumin (BSA), …