Phosphorylcholine antibodies preserve cardiac function and reduce infarct size by attenuating the post-ischemic inflammatory response
NJ Pluijmert, RCM de Jong, MR de Vries… - Basic to Translational …, 2020 - jacc.org
… This study investigated the modulatory effects of a fully human IgG1 monoclonal antibody
directed against phosphorylcholine (PC-mAb) on myocardial remodeling and cardiac function …
directed against phosphorylcholine (PC-mAb) on myocardial remodeling and cardiac function …
Antibodies against phosphorylcholine and malondialdehyde during the first two years of life
D Thiagarajan, SL Lundström, G Pershagen… - The Journal of …, 2020 - journals.aai.org
… Abs against phosphorylcholine (anti-PC) and Abs against malondialdehyde (anti-MDA) may
be protective in chronic inflammation, like atherosclerosis and cardiovascular disease. It is …
be protective in chronic inflammation, like atherosclerosis and cardiovascular disease. It is …
Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post‐ischaemic inflammatory response
NJ Pluijmert, RCM de Jong, MR de Vries… - Journal of Cellular …, 2021 - Wiley Online Library
… mice that a specific clone of IgM autoantibodies against phosphorylcholine, termed E06 or
T15 … IgM phosphorylcholine antibodies are associated with an increased risk of cardiovascular …
T15 … IgM phosphorylcholine antibodies are associated with an increased risk of cardiovascular …
Anti-phospholipid autoantibodies in human diseases
R Qin, H Wu, H Guan, C Tang, Z Zheng, C Deng… - Clinical …, 2023 - Elsevier
… anti-phospholipid autoantibody levels in patients with antiphospholipid syndrome, …
cardiovascular diseases. However, the underlying mechanisms of anti-phospholipid autoantibodies …
cardiovascular diseases. However, the underlying mechanisms of anti-phospholipid autoantibodies …
Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular 18F-FDG Uptake in Atherosclerotic Mice
M Ståhle, JMU Silvola, S Hellberg, M de Vries… - Basic to Translational …, 2020 - jacc.org
… -G1 antibody against phosphorylcholine on oxidized phospholipids preserves coronary flow
… to assess the efficacy of phosphorylcholine-targeted therapy on coronary artery function and …
… to assess the efficacy of phosphorylcholine-targeted therapy on coronary artery function and …
[PDF][PDF] … Anticardiolipin Antibody and IgG Antiphosphoryl choline levels in Serum of Patients have Chronic Periodontitis with and without Atherosclerotic Cardiovascular …
RA Radhi - 2019 - codental.uobaghdad.edu.iq
… anti-cardiolipin antibody and IgG antiphosphoryl choline) in (Atherosclerotic cardiovascular
… correlation between IgG Antiphosphoryl choline with IgM anticardiolipin antibody. Whereas, …
… correlation between IgG Antiphosphoryl choline with IgM anticardiolipin antibody. Whereas, …
[PDF][PDF] Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases
W Jukema, K Pettersson, PHA Quax - scholarlypublications …
… Previous data has shown that natural IgM anti-PC protect against cardiovascular disease.
We aimed to develop a monoclonal PC IgG antibody with anti-inflammatory and anti-…
We aimed to develop a monoclonal PC IgG antibody with anti-inflammatory and anti-…
Oxidized phospholipids in cardiovascular disease
S Tsimikas, JL Witztum - Nature Reviews Cardiology, 2024 - nature.com
… The natural mouse monoclonal antibody E06 recognizes the phosphocholine (PC) headgroup
of oxidized, but not native, phospholipids. Subtle conformational changes in the PC head …
of oxidized, but not native, phospholipids. Subtle conformational changes in the PC head …
Anti-phosphoryl Choline and hs-CRP in Serum of Atherosclerosis Cardiovascular Patient with Chronic Periodontitis..
RA Radhi, AO Ali ALmosawi - Indian Journal of Forensic …, 2020 - search.ebscohost.com
… Phosphorylcholine (PC) is an immunogenic epitope in the … patients exhibit elevated levels
of anti-PC and this antibody … phosphorylcholine (anti-phosphorylcholine IgG) in patients with …
of anti-PC and this antibody … phosphorylcholine (anti-phosphorylcholine IgG) in patients with …
Immune mechanisms and potential immunological treatment in atherosclerosis
SK Samal - 2022 - search.proquest.com
… autoantibodies anti-phoshorylcholine (anti-PC) and antimalondialdehyde (anti-MDA) and
their prevalence in cardiovascular disease (CVD) … on human anti-phosphorylcholine (anti-PC) …
their prevalence in cardiovascular disease (CVD) … on human anti-phosphorylcholine (anti-PC) …