… IgM is an antibody that appears in the body's initial immune response and is … patients with
stable CAD that linked very low concentrations of IgM antibodies against phosphorylcholine (…

… /1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphorylcholine, we generated a novel IgM
autoantibody, 10C12, from the spleens of Apoe –/– mice fed a long-term Western diet, that …

… Cardiovascular outcome studies and further basic science … antibody, generated in
atherosclerosis-prone Apoe −/− mice, has been shown to react with the head group of …

… A previous study showed that ESRD patients have a high … major determinant of cardiovascular
outcomes in these patients [18… protein 60, and to phosphorylcholine. Because anti-apoA-1 …

… patients with acute MI (AMI) is not well defined. We hypothesized that high titers of IgM
autoantibodies … To detect IgM autoantibodies binding to phosphocholine-bovine serum albumin (…

… antibody (4E6), according to the manufacturer’s instructions (Mercodia, Uppsala, Sweden).
The monoclonal antibody … Positively charged phosphocholine is shown in a green rectangle. …

… -glycero-3-phosphocholine] are elevated in the plasma of STEMI patients and are of interest
due … Moreover, since no antibody against lipids can be synthesized, constructing therapeutic …

… –IgG antibodies and acute coronary syndrome, suggesting an untoward role of this antibody
in plaque destabilization [16]. In human, oxLDL–specific IgG antibody titers correlated …

… auto-antibodies against ApoB in humans, we show that anti-ApoB IgG associate with
cardiovascular … responses against ApoB are shaped by cardiovascular risk factors but not disease …

… Evolocumab, a monoclonal antibody against PCSK9, lowers the levels of LDL-cholesterol …
In the structure of SM, the phosphocholine headgroup is bound to ceramide (Cer). …