A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein
… /damaged cell membranes via exposed phosphocholine lipid head groups. We … of
phosphocholine as a template. X‐ray crystallography revealed specific binding to the …
phosphocholine as a template. X‐ray crystallography revealed specific binding to the …
Oxidized phospholipid modification of lipoprotein (a): epidemiology, biochemistry and pathophysiology
ML Koschinsky, MB Boffa - Atherosclerosis, 2022 - Elsevier
… OxPL-apoB is measured by a chemiluminescent ELISA using E06, an IgM antibody
specific for OxPL containing a phosphocholine head group, and strongly associated with …
specific for OxPL containing a phosphocholine head group, and strongly associated with …
… anti-malondialdehyde modified peptide autoantibodies to import machine learning for predicting coronary artery stenosis in taiwanese patients with coronary artery …
YC Hsu, IJ Tsai, H Hsu, PW Hsu, MH Cheng, YL Huang… - Diagnostics, 2021 - mdpi.com
… predicting coronary artery disease (CAD). Our purpose was to utilize autoantibody isotypes
… In this study, levels of MDA, MDA-modified protein (MDA-protein) adducts, and autoantibody …
… In this study, levels of MDA, MDA-modified protein (MDA-protein) adducts, and autoantibody …
Lipidomics of bioactive lipids in acute coronary syndromes
… They also found that the monoclonal antibody E06, which binds to the phosphocholine head
group of PLs on Ox-LDL, inhibits Ox-LDL uptakes by macrophages [75]. Since then, several …
group of PLs on Ox-LDL, inhibits Ox-LDL uptakes by macrophages [75]. Since then, several …
Novel immunologic cellular mechanisms in atherosclerosis and potential therapeutic implications
MM Rahman - 2019 - openarchive.ki.se
… phosphorylcholine (PC) and MDA were correlated with a lower prevalence of atherosclerosis
among patients with … and purification of antibody specific for malondialdehyde (study I) or …
among patients with … and purification of antibody specific for malondialdehyde (study I) or …
Serum levels of antibodies against oxidation-specific epitopes are decreased in patients with retinal vein occlusion
L Posch-Pertl, M Weger, S Pinter-Hausberger, W List… - Retina, 2021 - journals.lww.com
… patients with RVO. We evaluated the serum levels of IgM and IgG antibodies to phosphocholine
… low density lipoprotein antibody levels indicate coronary heart disease and necrotic core …
… low density lipoprotein antibody levels indicate coronary heart disease and necrotic core …
[HTML][HTML] Sphingolipid Metabolism Is Associated with Cardiac Dyssynchrony in Patients with Acute Myocardial Infarction
CH Huang, CL Kuo, YS Cheng, CS Huang, CS Liu… - Biomedicines, 2024 - mdpi.com
… heart. Cardiac dyssynchrony is observed in patients with Fabry disease and left ventricular
(LV) hypertrophy. However, little information is available on the relationship between plasma …
(LV) hypertrophy. However, little information is available on the relationship between plasma …
Serum immunoglobulin M is associated with the severity of coronary artery disease in adults
Y Zhang, X Qi, S Wang, W Zhang, R Yang, X Wang… - PeerJ, 2024 - peerj.com
… Similarly, IgM titres to OSE phosphocholine have been reported to be inversely correlated
with the incidence of heart attack and CAD risk in patients with lupus (Anania et al., 2010; …
with the incidence of heart attack and CAD risk in patients with lupus (Anania et al., 2010; …
CARDIAC INJURY, ATHEROSCLEROSIS
JL Bock - Henry's Clinical Diagnosis and Management by …, 2021 - books.google.com
… It was only with the introduction of monoclonal antibody … proteins and phospholipids, particularly
phosphocholine. It opsonizes … cardiac troponin I concentration with cardiac outcomes in …
phosphocholine. It opsonizes … cardiac troponin I concentration with cardiac outcomes in …
Monomeric C-reactive protein in atherosclerotic cardiovascular disease: advances and perspectives
I Melnikov, S Kozlov, O Saburova, Y Avtaeva… - International journal of …, 2023 - mdpi.com
This review aimed to trace the inflammatory pathway from the NLRP3 inflammasome to
monomeric C-reactive protein (mCRP) in atherosclerotic cardiovascular disease. CRP is the final …
monomeric C-reactive protein (mCRP) in atherosclerotic cardiovascular disease. CRP is the final …