[HTML][HTML] Organoid and spheroid tumor models: Techniques and applications
S Gunti, ATK Hoke, KP Vu, NR London Jr - Cancers, 2021 - mdpi.com
… Organoids and spheroids are different 3D cell culture models … such applications as cancer
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
[HTML][HTML] Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties
… and represents the most common primary malignant brain tumor in adults with a median
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
Modelling Metastasis in Neuroblastoma: 3D Culture Assays of Local Tumour Invasion
C Gavin - 2022 - repository.rcsi.com
… culture and 3D invasion assays as a valuable tool to discover the molecular mechanisms
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
Molecular insights of metastasis and cancer progression derived using 3D cancer spheroid co-culture in vitro platform
… the cancer cells contributing in the advancement of the metastasis through 3D cancer spheroid
co-culture … Representative image of co-culture of cancer spheroids to study invasion. The …
co-culture … Representative image of co-culture of cancer spheroids to study invasion. The …
Spheroid glioblastoma culture conditions as antigen source for dendritic cell-based immunotherapy: spheroid proteins are survival-relevant targets but can impair …
F Erhart, T Weiss, S Klingenbrunner, K Fischhuber… - Cytotherapy, 2019 - Elsevier
… Glioblastoma is the most aggressive type of brain cancer. Dendritic cell (DC)-based …
condition-dependent antigen sources, we established an autologous model using glioblastoma cells…
condition-dependent antigen sources, we established an autologous model using glioblastoma cells…
[HTML][HTML] Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine
S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
… addition of non-autologous stromal/immune cells to 3D culture is … Similarly, brain tumor
spheroids were formed by seeding … into Matrigel to monitor the invasion of the extracellular matrix. …
spheroids were formed by seeding … into Matrigel to monitor the invasion of the extracellular matrix. …
High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment
B Calpe, WJ Kovacs - Expert opinion on drug discovery, 2020 - Taylor & Francis
… 3D cultures can vary in complexity from spheroids derived from a single cell line or … Finally,
heterotypic murine and patient-derived MTS containing cancer cells and autologous immune …
heterotypic murine and patient-derived MTS containing cancer cells and autologous immune …
[HTML][HTML] Neuroblastoma invasion strategies are regulated by the extracellular matrix
C Gavin, N Geerts, B Cavanagh, M Haynes… - Cancers, 2021 - mdpi.com
… yield of PDXs by isolating tumour organoids and growing them … invasion of NB organoids
by performing real-time 3D culture … used 3D in vitro spheroid models of NB invasion [64]. In …
by performing real-time 3D culture … used 3D in vitro spheroid models of NB invasion [64]. In …
[HTML][HTML] Trends and challenges in modeling glioma using 3D human brain organoids
A Mariappan, G Goranci-Buzhala… - Cell Death & …, 2021 - nature.com
… Glioma is an aggressive form of brain cancer characterized by poor … 3D culture systems to
study glioma invasion biology. … invasion assays between homologous and autologous assays …
study glioma invasion biology. … invasion assays between homologous and autologous assays …
[HTML][HTML] Evaluation of comprehensive gene expression and NK cell-mediated killing in glioblastoma cell line-derived spheroids
T Morimoto, T Nakazawa, R Matsuda, F Nishimura… - Cancers, 2021 - mdpi.com
… the most aggressive primary malignant brain tumor in adults. … culture conditions on a GBM
cell-derived 3D spheroid model. … 10% autologous plasma, 50 ng/mL recombinant human IL-18 …
cell-derived 3D spheroid model. … 10% autologous plasma, 50 ng/mL recombinant human IL-18 …