[HTML][HTML] Organoid and spheroid tumor models: Techniques and applications
S Gunti, ATK Hoke, KP Vu, NR London Jr - Cancers, 2021 - mdpi.com
… Organoids and spheroids are different 3D cell culture models … such applications as cancer
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
cell migration and invasion [32]. … organotypic tumor spheroids retaining autologous immune …
[HTML][HTML] Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties
… and represents the most common primary malignant brain tumor in adults with a median
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
survival … -based 3D culture model of GBM spheroids interacting with brain endothelial cells in …
Modelling Metastasis in Neuroblastoma: 3D Culture Assays of Local Tumour Invasion
C Gavin - 2022 - repository.rcsi.com
… culture and 3D invasion assays as a valuable tool to discover the molecular mechanisms
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
controlling local invasion … invasion utilise multicellular tumour spheroids (MCTS); aggregates of …
[HTML][HTML] Modeling human brain tumors and the microenvironment using induced pluripotent stem cells
… To more accurately model the human brain, a 3D culture … derived GSC spheroids exhibited
different invasion potential that … cells, this forms the basis for establishing autologous invasion …
different invasion potential that … cells, this forms the basis for establishing autologous invasion …
Developing bioinspired three-dimensional models of brain cancer to evaluate tumor-homing neural stem cell therapy
… tissue culture hood and incubated overnight in 3D cell culture … when designing redosing
studies and tracking tumor invasion. … In the case of autologous NSC-based therapies, a method …
studies and tracking tumor invasion. … In the case of autologous NSC-based therapies, a method …
[HTML][HTML] Glioblastoma organoids: pre-clinical applications and challenges in the context of immunotherapy
… For Glioblastoma (GBM), the most severe form of brain cancer … termed ‘organotypic tumor
spheroids’, these cultures fulfill the … vivo co-cultures of organoids with autologous PBMCs have …
spheroids’, these cultures fulfill the … vivo co-cultures of organoids with autologous PBMCs have …
[HTML][HTML] GD2 CAR T cells against human glioblastoma
M Prapa, C Chiavelli, G Golinelli, G Grisendi… - NPJ precision …, 2021 - nature.com
… on the delivery route for targeting brain tumors, we compared … C6) co-cultures with either
autologous or allogeneic GD2 … we used a biocompatible 3D cell culture device that allows a …
autologous or allogeneic GD2 … we used a biocompatible 3D cell culture device that allows a …
[HTML][HTML] Is it time to start transitioning from 2D to 3D cell culture?
… Hydrophilic glass fibers are important for modeling 3D tumors testing antibodies, invasion,
as well as tracking cell migration. SeedEZ discovered by Lena Biosciences is such an inert …
as well as tracking cell migration. SeedEZ discovered by Lena Biosciences is such an inert …
[HTML][HTML] Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine
S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
… addition of non-autologous stromal/immune cells to 3D culture is … Similarly, brain tumor
spheroids were formed by seeding … into Matrigel to monitor the invasion of the extracellular matrix. …
spheroids were formed by seeding … into Matrigel to monitor the invasion of the extracellular matrix. …
Spheroid glioblastoma culture conditions as antigen source for dendritic cell-based immunotherapy: spheroid proteins are survival-relevant targets but can impair …
F Erhart, T Weiss, S Klingenbrunner, K Fischhuber… - Cytotherapy, 2019 - Elsevier
… Glioblastoma is the most aggressive type of brain cancer. Dendritic cell (DC)-based …
condition-dependent antigen sources, we established an autologous model using glioblastoma cells…
condition-dependent antigen sources, we established an autologous model using glioblastoma cells…