Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies

F Porsch, Z Mallat, CJ Binder - Cardiovascular research, 2021 - academic.oup.com
… Associations of specific antibody levels and defined B-cell subsets … B cells and humoral
immunity in atherosclerotic cardiovascular disease. These include all aspects of B-cell immunity, …

[HTML][HTML] Immunity in atherosclerosis: focusing on T and B cells

AV Poznyak, EE Bezsonov, TV Popkova… - International Journal of …, 2021 - mdpi.com
… secrete poorly specific natural IgM antibodies, creating a rapid and T-cell-independent
humoral response. Secreted B1 antibodies are polyreactive and are the main defense against …

The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
… , IgG, and IgE as well as regulation of T cell responses affecting the progression of this disease,
… the spectrum of B cell involvement in dyslipidaemia and atherosclerosis. B cell receptors: …

[HTML][HTML] Functional role of B cells in atherosclerosis

SD Ma, M Mussbacher, EV Galkina - Cells, 2021 - mdpi.com
atherosclerosis-prone conditions. By summarizing current knowledge of B cells in and beyond
atherosclerosis… While OSE-derived antigens induce humoral response in atherosclerosis, …

B cells in atherosclerosis: mechanisms and potential clinical applications

T Pattarabanjird, C Li, C McNamara - Basic to Translational Science, 2021 - jacc.org
B cell–derived Igs modulate atherosclerosis, with a focus on the implications for potential
B-cell–targeted therapies for atherosclerotic … to induce a humoral response to limit the impact of …

[HTML][HTML] B cell and CD4 T cell interactions promote development of atherosclerosis

C Tay, P Kanellakis, H Hosseini, A Cao… - … in immunology, 2020 - frontiersin.org
… differentiation and production of high affinity immunoglobulins that play a critical role in
humoral response, we next assessed the effect of genetic deletion of immunoglobulin μ-heavy …

Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms

T Kyaw, P Loveland, P Kanellakis, A Cao… - European heart …, 2021 - academic.oup.com
atherosclerosis after MI and specifically identify key roles for alarmins in activating B cells
during MI; we also demonstrate that activated B cells … of established atherosclerosis to plaques …

Vaccination strategies and immune modulation of atherosclerosis

J Nilsson, GK Hansson - Circulation Research, 2020 - Am Heart Assoc
… The role of B cells in atherosclerosis is complex, with protective, as well as disease-…
reduces atherosclerosis, in apoe −/− as well as in ldlr −/− mice. Humoral immune responses …

How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
… Here, we review key molecular mechanisms of immune cell activation implicated … cells in
atherosclerosis are summarized in Box 2. The roles of antibodies and B cells in atherosclerosis

B lymphocytes and macrophages in the perivascular adipose tissue are associated with coronary atherosclerosis: an autopsy study

DS Farias‐Itao, CA Pasqualucci… - Journal of the …, 2019 - Am Heart Assoc
atherosclerosis. We hypothesized that the density of CD68 + macrophages, CD3 + T lymphocytes,
and CD20 + B lymphocytes … that the density of these immune cells would be greater in …