The role of B cells in atherosclerosis

AP Sage, D Tsiantoulas, CJ Binder… - Nature Reviews Cardiology, 2019 - nature.com
… that are abundant on modified lipoproteins and cellular debris. B cells control cellular
immune responses through cellcell contact, antigen presentation, and cytokine production, and …

B cells in autoimmune and neurodegenerative central nervous system diseases

JJ Sabatino Jr, AK Pröbstel, SS Zamvil - Nature Reviews Neuroscience, 2019 - nature.com
B cells in patients with MS express increased levels of T cell co-… associated with B cell
maturation and antigen presentation are … MHC class II-restricted antigen presentation by B cells is …

B cells, plasma cells and antibody repertoires in the tumour microenvironment

GV Sharonov, EO Serebrovskaya… - Nature Reviews …, 2020 - nature.com
… IgG1 + B cells in antigen presentation 45 . Such a high IgG1 proportion was also strongly
associated with longer survival in melanoma 43 , KRAS-mutant lung adenocarcinoma, and non-…

Tumour-infiltrating B cells: immunological mechanisms, clinical impact and therapeutic opportunities

CM Laumont, AC Banville, M Gilardi, DP Hollern… - Nature Reviews …, 2022 - nature.com
… -specific self-antigens by B cells and other TLS-associated antigen-presenting cells (APCs), …
, which play an integral role in antigen presentation to B cells in lymph nodes. It is unclear …

A guide to antigen processing and presentation

N Pishesha, TJ Harmand, HL Ploegh - Nature Reviews Immunology, 2022 - nature.com
antigen presentationB cells when it binds an antigen, it also internalizes the resulting
immune complex for processing and presentation via MHC-II molecules as a call for CD4 + T cell

Role of B cells in multiple sclerosis and related disorders

G Comi, A Bar‐Or, H Lassmann, A Uccelli… - Annals of …, 2021 - Wiley Online Library
… functions implicated in pathogenesis include (1) antigen presentation to T cells and driving
autoproliferation of brain-homing T cells (presumably by memory B cells), (2) production of …

B cell responses: cell interaction dynamics and decisions

JG Cyster, CDC Allen - Cell, 2019 - cell.com
… an overview of how B cells travel throughout the body surveying for antigen, how they respond
upon antigen encounter, how … The who, how and where of antigen presentation to B cells. …

Age-associated B cells

MP Cancro - Annual review of immunology, 2020 - annualreviews.org
B lymphoid lineage has facilitated analyses of the cellular and molecular events key to lineage
specification, B cell antigen … regulatory cytokine production, antigen presentation, and the …

B cell memory: building two walls of protection against pathogens

M Akkaya, K Kwak, SK Pierce - Nature Reviews Immunology, 2020 - nature.com
… and detailed knowledge of the VRC01-class B cell antigen, this … B cells expressing germline
VRC01-class BCR (~1 in 10 6 ), antigen affinity (less than 1 μM) and avidity (an antigenic

Antigen processing and presentation

F Kotsias, I Cebrian, A Alloatti - International review of cell and molecular …, 2019 - Elsevier
… the different antigen presentation pathways used by … cell types, MHC class II molecules are
constitutively expressed in few immune cells, such as DCs, macrophages and B lymphocytes. …