Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification

P Soares, AA Povoa, M Melo, J Vinagre, V Maximo… - Endocrine …, 2021 - Springer
… clarified the pathogenesis, at the molecular level, of thyroid carcinomas and … BRAF
V600E-mutated PTC [26] (Table 1). The association of BRAF mutation and PTC at advanced clinical

BRAF inhibitors in thyroid cancer: clinical impact, mechanisms of resistance and future perspectives

F Crispo, T Notarangelo, M Pietrafesa, G Lettini… - Cancers, 2019 - mdpi.com
… in the pathogenesis of thyroid cancer. As a multi-kinase inhibitor, sorafenib potentially inhibits
Clinically, BRAF V600E -mutated thyroid cancer cells exhibit primary resistance or poor …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - … (BBA)-Reviews on Cancer, 2023 - Elsevier
… in clinical research, and explore potentially novel molecular … of BRAF mutation indicate that
the mutation may play a key role … are at the core of TC pathogenesis and progression [11]. …

Update on fundamental mechanisms of thyroid cancer

A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
… discusses the molecular mechanisms associated to the pathogenesis of different types of TC
and their clinical relevance. … BRAF mutations are associated with some histological types of …

Molecular alterations in thyroid cancer: from bench to clinical practice

E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
… classify the molecular alterations detected in thyroid cancer, … thyroid carcinogenesis that
involve pivotal cellular functions. … The most common BRAF mutation is the V600E substitution, …

BRAF V600E mutation in papillary thyroid cancer is correlated with adverse clinicopathological features but not with iodine exposure

S Özçelik, R Bircan, Ş Sarıkaya, AE Gül… - Endokrynologia …, 2019 - journals.viamedica.pl
… abnormality in the pathogenesis of papillary thyroid carcinoma. We aimed to … Clinical and
histopathological profile of BRAF V600E mutation in conventional papillary thyroid carcinoma

Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
… of the molecular pathogenesis underlying thyroid cancer … changes in the clinical management
of thyroid nodules, and … the oncogenic role of BRAF V600E and TERTp mutations, it …

BRAF and TERT promoter mutations: clinical application in thyroid cancer

JH Chung - Endocrine Journal, 2020 - jstage.jst.go.jp
… It is frequently activated in thyroid cancer through BRAF mutation, RAS mutation, and RET/…
) BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical

BRAF and KRAS mutations in papillary thyroid carcinoma in the United Arab Emirates

S Al-Salam, C Sharma, B Afandi, K Al Dahmani… - PLoS …, 2020 - journals.plos.org
… in PTC and their correlation with clinical and pathological … family history of thyroid cancer and
BRAF V600E mutation (P = 0.… player in the pathogenesis of PTC, as somatic mutations in its …

Association between BRAF (V600E) mutation and clinicopathological features of papillary thyroid carcinoma: a Brazilian single-centre case series

D Pessôa-Pereira, MFS Medeiros, VMS Lima… - … of Endocrinology and …, 2019 - SciELO Brasil
BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical
Time to re-consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma. Int …