Anaplastic thyroid carcinoma: an update

A Jannin, A Escande, A Al Ghuzlan, P Blanchard… - Cancers, 2022 - mdpi.com
… differed from the ones in papillary DTC. This led to the … are limited to PDTC and ATC,
suggesting a role in tumor progression [… stemness and metastasis by activating the PI3K/AKT/mTOR …

Impact of somatic mutations on survival outcomes in patients with anaplastic thyroid carcinoma

JR Wang, M Montierth, L Xu, M Goswami… - JCO Precision …, 2022 - ascopubs.org
Papillary thyroid carcinoma (PTC) was the most common … of metastasis seen in follicular and
Hurthle cell thyroid cancers. … melanoma, the duration of response was limited with a PFS of …

Histological features of BRAF V600E‐mutant anaplastic thyroid carcinoma

TY Chen, JH Lorch, KS Wong, JA Barletta - Histopathology, 2020 - Wiley Online Library
papillary thyroid carcinoma (PTC), BRAF V600E IHC strongly correlates with BRAF mutation
… Thus, it is important to consider how our results could be extrapolated for cases with limited

Anaplastic thyroid carcinoma: Current issues in genomics and therapeutics

I Abe, AK Lam - Current Oncology Reports, 2021 - Springer
thyroid carcinoma had no BRAF mutations [2•]. This report revealed most BRAF V600E
mutations were detected in papillary thyroid … with anaplastic thyroid carcinomas [75] but is limited

[PDF][PDF] Concurrent anaplastic and papillary thyroid carcinomas: a case report

S Skwiersky, G Hevroni, G Singh, L Hope… - Am J Med Case …, 2020 - academia.edu
… been documented to have mutations in the BRAF V600 gene, … the BRAF V600E mutation,
further rendering BRAF mutations … Given the limited systemic therapeutic options available for …

Molecular therapeutics for anaplastic thyroid cancer

N Pozdeyev, MM Rose, DW Bowles… - Seminars in cancer …, 2020 - Elsevier
… as papillary or follicular thyroid cancer in the same thyroid gland. … also had concomitant
well-differentiated carcinomas [3]. It has … was restricted to tumors with BRAF V600E mutations and …

Targeted therapy with vemurafenib in BRAF (V600E)-mutated anaplastic thyroid cancer

M Lang, T Longerich, C Anamaterou - Thyroid Research, 2023 - Springer
… benefit of BRAF inhibition in BRAF-mutated ATC, limited by … a papillary thyroid carcinoma
with a positive BRAF-mutation (… than that in papillary carcinomas [83]. In a mouse model, the …

[HTML][HTML] Novel treatments for anaplastic thyroid carcinoma

SM Ferrari, G Elia, F Ragusa, I Ruffilli, C La Motta… - Gland …, 2020 - ncbi.nlm.nih.gov
… human cancers and it is less than 2% of thyroid carcinomas (TCs). … ) were associated with
limited disease progression. Moreover… BRAF mutation in papillary thyroid carcinoma: predictive …

Genetic alterations in anaplastic thyroid carcinoma

M Rashid, A Agarwal, R Pradhan… - Indian Journal of …, 2019 - journals.lww.com
… The most common BRAF V600E mutation reported in thyroid carcinomas is confined to …
has been documented to be the most common mutation in papillary thyroid cancer.[ 16 17 ] The …

Dissecting anaplastic thyroid carcinoma: a comprehensive clinical, histologic, immunophenotypic, and molecular study of 360 cases

B Xu, T Fuchs, S Dogan, I Landa, N Katabi, JA Fagin… - Thyroid, 2020 - liebertpub.com
… Other variants of papillary thyroid carcinoma documented in … tested for both BRAF V600E
immunostain and BRAF mutationmetastasis, including 83 patients with distant metastasis at …