[HTML][HTML] BRCA1-and BRCA2-associated hereditary breast and ovarian cancer
N Petrucelli, MB Daly, T Pal - 2022 - europepmc.org
N Petrucelli, MB Daly, T Pal
2022•europepmc.orgBRCA1-and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is
characterized by an increased risk for female and male breast cancer, ovarian cancer
(including fallopian tube and primary peritoneal cancers), and to a lesser extent other
cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals
with a BRCA2 pathogenic variant. The risk of developing an associated cancer varies
depending on whether HBOC is caused by a BRCA1 or BRCA2 pathogenic variant.
characterized by an increased risk for female and male breast cancer, ovarian cancer
(including fallopian tube and primary peritoneal cancers), and to a lesser extent other
cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals
with a BRCA2 pathogenic variant. The risk of developing an associated cancer varies
depending on whether HBOC is caused by a BRCA1 or BRCA2 pathogenic variant.
BRCA1-and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for female and male breast cancer, ovarian cancer (including fallopian tube and primary peritoneal cancers), and to a lesser extent other cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals with a BRCA2 pathogenic variant. The risk of developing an associated cancer varies depending on whether HBOC is caused by a BRCA1 or BRCA2 pathogenic variant.
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