Sex dimorphism and tissue specificity of gene expression changes in aging mice
… alterations, genomic instability and splicing dysregulation result in gene expression …
Brie y, we performed 20 runs of multivariate logistic regression with elastic net regularization…
Brie y, we performed 20 runs of multivariate logistic regression with elastic net regularization…
[PDF][PDF] Genome-wide screening of m6A-modified transcript in the Wilms' tumor
Z Liu, F He, J Liu, S OuYang, Z Li, Y Li, F Ma, H Chang… - 2021 - scholar.archive.org
… In the present study, we provide the rst transcriptome-wide m6A pro le of nephroblastoma. …
, and PTEN, were analyzed by quantitative real-time PCR (qRT-PCR). Brie y, total RNA was …
, and PTEN, were analyzed by quantitative real-time PCR (qRT-PCR). Brie y, total RNA was …
[PDF][PDF] The translatome of Glioblastoma multiforme
FMG Cornelissen, A He, RR Haas, M Houweling… - 2023 - scholar.archive.org
… of histones is inhibited while splicing factors are more intensively … , recently updated
based on single cell analyses45. To identify … McGlincy, NJ & Ingolia, NT Transcriptome-wide …
based on single cell analyses45. To identify … McGlincy, NJ & Ingolia, NT Transcriptome-wide …
Differentially expressed genes in ethanol extract of vanilla planifolia stem-induced cell death in glioblastoma cells
HH Chang, YJ Chen, SG Wu, LJ Chen, BC Tsai… - 2023 - researchsquare.com
… Brie y, TRIzol Reagent was used to lyse VAS-treated cells. Total RNA was then puri ed …
In a transcriptome-wide association study, low src kinase-associated phosphoprotein 1 (SKAP1) …
In a transcriptome-wide association study, low src kinase-associated phosphoprotein 1 (SKAP1) …
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia
J Bajaj, M Hamilton, Y Shima, K Chambers, K Spinler… - Nature Cancer, 2020 - nature.com
Aggressive myeloid leukemias such as blast crisis chronic myeloid leukemia and acute myeloid
leukemia remain highly lethal. Here we report a genome-wide in vivo CRISPR screen to …
leukemia remain highly lethal. Here we report a genome-wide in vivo CRISPR screen to …
Bayesian statistical learning for big data biology
C Yau, K Campbell - Biophysical reviews, 2019 - Springer
… individual cells. However, the challenge when working with single cells is the inherent sensitivity
of cells … A related analysis is identifying differential splicing in which exon usage varies …
of cells … A related analysis is identifying differential splicing in which exon usage varies …
DeepLocRNA: an interpretable deep learning model for predicting RNA subcellular localization with domain-specific transfer-learning
… Ideally, measuring transcriptome-wide RNA– protein interactions would deliver a broad
interaction profile between RBPs and RNAs, revealing the numerous regulatory aspects of co- …
interaction profile between RBPs and RNAs, revealing the numerous regulatory aspects of co- …
The Genetic Architecture of Dietary Iron Overload and Associated Pathology in Mice
BK Fuqua, L Moses, S McLachlan, C Pan, RC Davis… - bioRxiv, 2023 - biorxiv.org
… We thus examined genes to find those whose cis component of expression variance correlates
significantly (bicor P < 0.05) with each trait, which we refer to here as transcriptome wide …
significantly (bicor P < 0.05) with each trait, which we refer to here as transcriptome wide …
N6-Methyladenosine Modification Changes in the Genome of Paulownia Fortunei Seedlings Infected With Phytoplasma
P Xu, S Huang, X Zhai, X Li, H Yang, Y Cao, G Fan - 2022 - researchsquare.com
… splicing events in PaWB-infected Paulownia. The combined … Brie y, approximately 300 mg
total RNA was extracted and … Transcriptome-wide mapping of N6methyladenosine by m6A-…
total RNA was extracted and … Transcriptome-wide mapping of N6methyladenosine by m6A-…
De novo mutations in bipolar disorder implicate neurodevelopment, immunity, and synaptic signaling
T Shimada, R Smith, H Sung, E Besancon, F Lopez… - 2023 - researchsquare.com
… Brie y, topic modeling is a text mining method for unsupervised classi cation of text. The …
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder…
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder…