Transcriptome and whole genome sequencing profiles in Leber's Hereditary Optic Neuropathy 14484T> C mutation carrying monozygotic twins reveal that prostanoid …

KKZ Tun, J Toosaranont, S Kaewsutthi, H Grove… - 2021 - researchsquare.com
Brie y, broblasts were seeded and treated with different culture condition in the same fashion
as the treatment protocol for cell viability assay. Fibroblasts were subsequently stained with …

Systematical comparison reveals distinct brain transcriptomic features in models of depression induced by gut microbiota dysbiosis and chronic stress

S Gui, Y Liu, J Pu, D Wang, X Zhong, W Chen, X Chen… - 2024 - researchsquare.com
Brie y, we generated a cell type signature matrix using smart-seq data from ALLEN BRAIN
MAP (https://portal.brain-map.org/), including six cell types (including GABAergic neuron, …

Characterization of an RNA binding protein interactome reveals the targetable post-transcriptional landscape of MYC-amplified medulloblastoma

M Kameda-Smith, H Zhu, EC Luo, C Venugopal… - 2022 - researchsquare.com
… & Burge, CB Identi cation and analysis of alternative splicingSingle cells were plated in 96
wells, at a density of 100-2000 … The methodology was rst described by Lovci et al116; brie y …

The genetic architecture of pain intensity in a sample of 598,339 US veterans

H Kranzler, S Toikumo, R Vickers-Smith, Z Jinwala… - 2023 - researchsquare.com
Brie y, DNA samples were removed for sex mismatch, having … -component analysis (PCA)-adjusted
method and within oneTranscriptome-wide association study (TWAS) and proteome-…

Transcriptome Analysis of Black and White Sesame Seed Reveals Candidate Genes Associated with Black Seed Development in Sesame (Sesamum Indicum)

SSK Dossou, L Wang, X Wei, Y Zhang, D Li, J Yu… - 2020 - researchsquare.com
… for transcriptome-wide analysis of differential gene expression and differential splicing of …
Brie y, each sample total RNA was extracted with the TRIzol reagent (Invitrogen Corp.). After …

Genome-wide analysis of long non-coding RNAs (lncRNAs) in two contrasting soybean genotypes subjected to phosphate starvation

H Xu, Y Yang, X Zhang, Z Huang, D Zhang - 2021 - researchsquare.com
… 20 to 24 nucleotides that are generated from a single-stranded RNA precursor with a hairpin
secondary structure. LncRNAs can be spliced by miRNAs into multiple small RNAs, and as …

Bioinformatic analysis of methyltransferase-like protein family reveals clinical and functional outcomes in human cancer

I Campeanu, Y Jiang, M Pilecki, A Najor, E Cobani… - 2021 - researchsquare.com
… Loss-of-function analysis in tumor cell lines indicated the biological importance of METTL1,
… cancer cell growth and survival. Furthermore, functional annotation and pathway analysis of …

A novel human monogenic obesity trait: severe early-onset childhood obesity caused by aberrant expression of agouti-signaling protein (ASIP): a case report

A Körner, E Kempf, R Stein, M Hanschkow, A Hilbert… - 2022 - researchsquare.com
… in the patient’s SVF cells through transcriptome-wide analyses. … Brie y, AT was washed in
phosphate-buffered saline (PBS) (… Single cell trajectory analysis of human pluripotent stem …

[图书][B] The Integration of Time of Day and Temperature Stress in Plant Transcriptomics

K Laosuntisuk - 2022 - search.proquest.com
… Although a full evaluation of transcriptome-wide regulation under circadian conditions has
not been evaluated, the functional components of the circadian clocks have been investigated …

[PDF][PDF] Forced expression of the non-coding RNA miR-17∼ 92 restores activation and function in CD28-deficient CD4+ T cells

M Dölz, M Hasiuk, JD Gagnon, M Kornete, R Marone… - Iscience, 2022 - cell.com
… of a single copy of the miR-17$92 transgene in CD28À/À cells. In addition, we directly
compared the effect of the miR-17$92 transgene in CD28-deficient and CD28-sufficient T cells in …