… arise from a single cell, which is known as the monoclonal origin of tumors. However, there
… has been studied using RNA-sequencing, which enables transcriptome-wide profiling of the …

… Transcriptome-wide … 2,800 single cells, identifying thousands of cell-speci c novel isoforms
and di erential isoform usage between cell lines for genes enriched in mRNA splicing and cell…

… Brie y, m6A RNA immunoprecipitation was performed with … Su et al. rstly identi ed the
transcriptome-wide map of m6A … quantitatively compared transcriptome-wide changes between …

… Since a particular splice junction may appear in more than one mRNA isoform, we design
DCEN to be invariant to the splice junctions. In the following § 5.1, we discuss the key …

… can affect mRNA transcription, splicing, translation and stability [12… Brie y, fragmented RNA
was incubated in buffer and the … laevis, we examined the transcriptome-wide m6A modi cation …

… Brie y, this approach uses targeted expression of a cytosine … of each are heavily biased
toward one cell type or the other and … targets, we also obtained transcriptome-wide mRNA decay …

… (RNA-seq) analysis of alternative splicing is its reliance on high … CLIP-seq analysis of AGO2
allows transcriptome-wide … inclusion/skipping levels in bulk tissues or single cells (8-11), we …

… , and has retarded the transcriptome-wide discovery of miRNAs … work through regulating
alternative splicing or transcriptional … Brie y, small RNAs were reversed transcribed and ampli ed …

… one frequently used unproductive splicing event in oligoadenylate synthetase 1g (Oas1g),
an important murine anti-viral response factor, and show that removal of the alternative splice …

A single “typo” in the genome can have profound consequences on an organism’s biology.
Identifying the protein changes that accompany these genomic typos is a fundamental …