Modulation of spatial memory and expression of hippocampal neurotransmitter receptors by selective lesion of medial septal cholinergic and GABAergic neurons

MG Dashniani, MA Burjanadze… - Experimental Brain …, 2020 - Springer
… The obtained results revealed that in contrast to cholinergic lesions, ratsbehavioral
experiments, special attention is deserved for the assessment of the effect of selective immunolesion

[HTML][HTML] Cholinergic deficit induced by central administration of 192IgG-saporin is associated with activation of microglia and cell loss in the dorsal hippocampus of …

YV Dobryakova, MN Volobueva… - Frontiers in …, 2019 - frontiersin.org
… and astrocytes using immunohistochemistry and neuroglial gene … considered as a factor
promoting damage to neurons, was … immunolesion of cholinergic neurons in the basal forebrain. …

Modulation of prefrontal cortex function by basal forebrain cholinergic and GABAergic neurons at the behavioral and molecular level

GV Beselia, NC Chkhikvishvili, MA Burjanadze… - …, 2021 - journals.lww.com
… to study the effects of selective immunolesions of cholinergic or … The rats were divided into
three groups: the NBM cholinergic… The immunohistochemical experiments revealed that an …

Acetylcholine and noradrenaline differentially regulate hippocampus-dependent spatial learning and memory

G de Leo, R Gulino, M Coradazzi… - Brain …, 2023 - academic.oup.com
… a cholinergic–noradrenergic dual immunolesioning approach … which then underwent extensive
behavioural analyses during … ablating cholinergic neurons in the BF of immature rats did …

[HTML][HTML] Protective Effects of a synthetic glycosaminoglycan mimetic (OTR4132) in a rat immunotoxic lesion model of septohippocampal cholinergic degeneration

PM Pereira, D Papy-Garcia, D Barritault… - Glycoconjugate …, 2022 - Springer
… criteria: (i) partial cholinergic damage reproducible in terms of both … immunolesion was
monitored using AChE histochemistry in the hippocampus and anti-ChAT immunohistochemistry

Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of …

JI Soares, C Da Costa, MH Ferreira, PA Andrade… - Brain Research, 2019 - Elsevier
… significant alterations in the activity of cholinergic neurons. … of cholinergic plasticity, at least
half of the rats in SAP + KA group showed spontaneous seizures and had severe behavioral

Nitric oxide donor molsidomine promotes retrieval of object recognition memory in a model of cognitive deficit induced by 192 IgG-saporin

MA Hernández-Melesio, M Alcaraz-Zubeldia… - Behavioural brain …, 2019 - Elsevier
… the immunohistochemical detection of ChAT-positive cholinergiccholinergic neurons loss
induced in the 192-IgG-SAP rat model, but prevented the progression of the neuronal damage

Cholinergic Modulation of Behaviour

O Kljakic - 2021 - search.proquest.com
cholinergic nuclei modulate behavioural functions. To do that we selectively eliminated
acetylcholine (ACh) release from cholinergic … behaviours using classical behavioural tests as well …

[HTML][HTML] Neuroprotective role of dietary supplementation with omega-3 fatty acids in the presence of basal forebrain cholinergic neurons degeneration in aged mice

D Cutuli, E Landolfo, D Decandia, A Nobili… - International Journal of …, 2020 - mdpi.com
… before cholinergic depletion can counteract behavioral … astrogliosis in agreement with findings
in rats and AD patients. In fact, … been shown that following a brain injury there is a synaptic …

Use of 192 IgG-saporin as a model of dementia and its application

JW Chang, YS Park - Genetics, Neurology, Behavior, and Diet in Dementia, 2020 - Elsevier
… toxicity to cholinergic neurons in the basal forebrain of rats. … to cholinergic neurons expressing
p75 without damaging … adult hippocampal neurogenesis (immunohistochemical stain with …