… Synergy between the 5ʹ cap and the 3ʹ poly(A) tail further … These interactions stabilize
eIF4E on the cap 58 and could … shortened, its affinity for Pan2–Pan3 progressively decreases. It …

… of mRNAs might stabilize the cap•eIF4E•eIF4G•PABP•poly(A) complex and enhance cap-poly(A)
translational synergy. … , yeast extract, and in rabbit reticulocyte lysate (RRL) suggest that …

… and eIF4E-eIF4G-PABP–poly(A) complex, through interactions in … We measured the binding
affinities of PABP WT and PABP 4EA … PABP from rabbit reticulocyte lysates was confirmed by …

… Subsequently, the synergy between eukaryotic mRNA 5’ cap … the absence of the canonical
cap/eIF4E/eIF4G/PABP/poly(A) … the capped 5’ end and the 3’ poly(A)-tail of eukaryotic mRNA …

… , associated with the 5' end of mRNA, interact with proteins … this interaction in the translation
in rabbit reticulocytes lysate … of closed-loop structure (eIF4E–eIF4G–PABP). Thus, the …

… and biochemical evidence supporting the functional synergy … eIF4F then is brought into
proximity with the 5′ end of the … with eIF4E for the 5′ cap, thus inhibiting mRNA translation (…

… the functional affinity of eIF4E for the capped mRNA 5′-end. … to decrease termination
efficiency and second by interacting with eRF3 to increase the efficiency of postTC formation, even …

… the 7-methylguanosine cap located at the 5’ end of the mRNA. … Replication of the cap-poly(A)
synergistic system in vitro … cell extracts, while in rabbit reticulocyte lysates, PABPC1 had the …

… , these are two distinct biochemical processes. In this review, … process starts with eIF4E
binding to the mRNA 5’ cap, which … of Pol II near the gene 5’ end. Thus, sppRNA features are …

… interact with various proteins involved in the biogenesis and … We find that distinct sets of
messenger RNA (mRNA) and non-… lysate IPs, cDNA libraries from three independent biological …