CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway

KU Bicalho, MM Santoni, P Arendt… - Plant and Cell …, 2019 - academic.oup.com
… of the quinone methide triterpenoid biosynthesis pathway. … of the quinone methide
triterpenoid biosynthesis pathway, … of friedelanes and ultimately quinone methide triterpenoids. …

[PDF][PDF] Lorena Diniz Guimarães1, 2, Fernanda Moreira do Amaral2, 3, Natalia Barros dos Santos2, Ana Joffily2

MC Anholeti, SR de Paiva - Rodriguésia, 2020 - academia.edu
… Due to their great occurrence and structural variety in Maytenus sl, triterpenes were chosen
as chemosystematic markers, with friedelanes and quinone methide triterpenes being the …

A chemophenetic study of the genus Maytenus sl (Celastraceae): contribution to the rational search of its bioactive metabolites

LD Guimarães, FM Amaral, NB Santos, A Joffily… - Rodriguésia, 2020 - SciELO Brasil
… markers, with friedelanes and quinone methide triterpenes being the most expressive … )
Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus

Modulation of quinonemethide triterpenes biosynthesis in Monteverdia floribunda (Reissek) biral root cultures by exogenous inhibitors

M Valdevite, BW Bertoni, EJ Crevelin, L Biral… - Plant Cell, Tissue and …, 2022 - Springer
… The goal of this work was to evaluate the effect of inhibitors on quinonemethide triterpenes
production from M. floribunda roots in vitro, besides the biosynthetic route was confirmed. …

Investigation of studies involving the prospection of chemical compounds with antioxidant and antimicrobial potential from maytenus guianensis Klotzsch Ex Reissek …

NA de Sá Holanda… - …, 2024 - ojs.observatoriolatinoamericano …
… , and one of these species is Maytenus guianensis, popularly known as chichuá, xixuá, …
friedelane triterpene, 29-hydroxyfriedelan-3-one triterpene, 16βhydroxyfriedelan-3-one triterpene

[PDF][PDF] Friedelin synthase from Maytenus ilicifolia: Leucine 482 Plays an Essential Role in the Production of the Most Rearranged Pentacyclic triterpene

CF Zanelli - academia.edu
… be the precursor of antitumoural quinone methide triterpenoids, including maytenin and …
Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus

The Methionine 549 and Leucine 552 Residues of Friedelin Synthase from Maytenus ilicifolia Are Important for Substrate Binding Specificity

BF Mazzeu, TM Souza-Moreira, AA Oliveira… - Molecules, 2021 - mdpi.com
triterpene found in the leaves of the Celastraceae species, demonstrates numerous biological
activities and is a precursor of quinonemethide triterpenes, … in the triterpene biosynthetic

Friedelin: Structure, Biosynthesis, Extraction, and Its Potential Health Impact

SK Singh, S Shrivastava, AK Mishra, D Kumar… - Molecules, 2023 - mdpi.com
… Friedelin (friedelan-3-one) is a pentacyclic triterpene isolated … compounds of these friedelane
triterpenoids are abundantly … Rosaceae and Maytenus ilicifolia and Maytenus aquifolium of …

Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the 13C-NMR Data

KC Camargo, MG de Aguilar, ARA Moraes… - Molecules, 2022 - mdpi.com
… possess friedelane, oleanane, lupane, ursane and quinonemethide skeletons. Quinonemethides
are … Simplified terpenoid biosynthetic route for the formation of the main pentacyclic …

Probing the functions of friedelane‐type triterpene cyclases from four celastrol‐producing plants

Y Lu, Y Luo, J Zhou, T Hu, L Tu, Y Tong, P Su… - The Plant …, 2022 - Wiley Online Library
… representative friedelane-type triterpenoid with a quinone-methide … The two compartmentalized
pathways can produce … in the biosynthesis of various triterpenes, such as friedelane-, …