Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
… activation in the bladder and bladder afferent pathways, could be a potential treatment that
… urothelium and smooth muscles, leading to stimulation of bladder afferents and induction of …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
bladder is initially areflexic but then becomes hyperreflexic … , inducing initially an areflexic
bladder leading to urinary … Aδ-fiber bladder afferent pathways to enhance the bladder-to-…

Autonomic dysreflexia following spinal cord injury

V Balik, I Šulla - Asian Journal of Neurosurgery, 2022 - thieme-connect.com
… in blood pressure induced by afferent sensory stimulation owing to … , also known as autonomic
hyperreflexia, AD syndrome, or … by the distension of urinary bladder, genitourinary tract …

Intraspinal plasticity associated with the development of autonomic dysreflexia after complete spinal cord injury

FM Michael, SP Patel, AG Rabchevsky - Frontiers in Cellular …, 2019 - frontiersin.org
… between injury-induced sprouting of pelvic visceral afferent C-… pathways disrupted/rerouted
by complete spinal cord injury (… Sensory afferent fibers (blue) from the distended bladder or …

… facilitation of the spinal locomotor central pattern generator and reflex circuits by somatosensory feedback from the lumbar and perineal regions after spinal cord injury

AN Merlet, J Harnie, A Frigon - Frontiers in Neuroscience, 2021 - frontiersin.org
… of urine in the bladder, as we thoroughly empty the bladders … brain that induces and maintains
plasticity in the spinal cord. … foot afferents, as well as the potential mechanisms involved. …

Deciphering spinal endogenous dopaminergic mechanisms that modulate micturition reflexes in rats with spinal cord injury

S Hou, JH DeFinis, SL Daugherty, C Tang… - Eneuro, 2021 - eneuro.org
… However, injection of L-DOPA unmasks HFOs in bladder pressure and induces a longer …
bladder hyperreflexia by first activating inhibitory DR 1 expressed on C-fiber bladder afferents

… involvement of noradrenergic neuronal neurotransmitter release in cutaneous vasoconstriction during autonomic dysreflexia in persons with spinal cord injury

M Trbovich, Y Wu, T Romo, W Koek, D Kellogg - Autonomic Neuroscience, 2024 - Elsevier
cord amplifies noious afferent input from bowel/bladder … along the entire efferent sympathetic
pathways including the spinal … -induced VC, our results indicate that another mechanism, …

Spinal Cord Injury Causes Marked Tissue Rearrangement in the Urethra—Experimental Study in the Rat

A Ferreira, SS Chambel, A Avelino… - International Journal of …, 2022 - mdpi.com
… the bladder and urethral sphincter contraction, causing urinary … While the sprouting of bladder
afferents has been linked to … a pattern of bladder hyperreflexia. Urodynamic parameters, …

[HTML][HTML] Multi-session transcutaneous spinal cord stimulation prevents chloride homeostasis imbalance and the development of hyperreflexia after spinal cord injury in …

DC Malloy, MP Côté - Experimental neurology, 2024 - Elsevier
… the SCI-induced disruption in chloride homeostasis in lumbarBladders were manually
expressed at least twice a day for … activating sensory afferents, this suggests that tSCS likely acts …

… and bladder inflammation in urinary tract infection, bladder pain syndrome with interstitial cystitis and neurogenic lower urinary tract dysfunction in spinal cord injury …

M Wyndaele, A Charrua, F Hervé… - Neurourology and …, 2023 - Wiley Online Library
… changes, and is a potential mechanism for (neurogenic) detrusor … induced bladder
permeability evokes bladder afferent … Attenuating neurogenic sympathetic hyperreflexia robustly …