… have shown that blocking sepsis-induced DC apoptosis or … apoptosis could be a new
therapeutic approach in sepsis. Further, exploring potential therapeutic targets related to apoptosis …

… organs during sepsis, and an inhibition of apoptosis by using … identification of infections,
rational employment of antibiotics, … -1/PD-L1 blockade can be used to treat sepsis. To investigate …

… to consider that a single therapeutic strategy or medication would provide … , blocking
PD-1/PD-L1 pathway with anti-PD-1 or anti-PD-L1 antibodies in septic patients decreased apoptosis …

… sepsis patients by suppressing monocytes, neutrophils and effector T cells [5]. Therefore, the
reversal of lymphocyte apoptosis is a challenging aspect of sepsis treatment. … and blockade …

… to the induction of abnormal apoptosis in different organs, … therapeutic strategies may be
employed to treat sepsis, or at … growth of sepsis-induced bacteria, (2) blocking the binding of …

… with anti-CTLA4 antibody attenuates T cell apoptosis and improves survival in CLP induced
sepsis (… therapeutic approach using immune checkpoint blockade in conjunction with other …

… ER mediated cell apoptosis, was reestablished by melatonin, probably through the MAPK/ERK
pathway (66). Lastly, melatonin protects mitochondria by blocking the overexpression of …

… , causing apoptosis/necrosis of … infection often causes lesions that are located in lower
lobes instead of upper lobes, and progresses more rapidly compared with SARS-CoV infection…

… search on therapeutic strategies aiming at treating sepsis or … Several authors have described
the effect of C5a blockade in … ), anti-C5a treatment lowered thymocyte apoptosis by 80%. …

… the rationality of nanoplatforms in sepsis management is … sepsis and future therapeutic
concepts, summarizing the progress of these well-designed nanoplatforms in sepsis management …