Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis

H Zhang, L Liu, JJ Ni, XT Wei, GJ Feng, XL Yang… - Osteoporosis …, 2020 - Springer
Bone mineral density (BMD) and bone size (BS) are two important factors that contribute to
the development of osteoporosis and osteoporotic fracturegenome-wide association studies (…

Prioritization of Osteoporosis Associated Genome wide Association Study (GWAS) Single Nucleotide Polymorphisms (SNPs) Using Epigenomics and Transcriptomics

X Zhang, HW Deng, H Shen… - … and Mineral Research …, 2021 - academic.oup.com
… examined in many genome wide association studies (GWASs… relevant to osteoporosis from
38 reported bone mineral density (… with low BMD, osteoporotic fractures in elderly individuals, …

Genome-wide association study identifies genetic variants which predict the response of bone mineral density to teriparatide therapy

N Alonso, OME Albagha, A Azfer… - Annals of the …, 2023 - ard.bmj.com
osteoporosis as part of everyday clinical practice. As TPTD is used both as a primary treatment
in patients for severe osteoporosis … of patients in the genome wide association analysis (…

[HTML][HTML] Comprehensive analysis of the genetic and epigenetic mechanisms of osteoporosis and bone mineral density

H Dong, W Zhou, P Wang, E Zuo, X Ying… - Frontiers in Cell and …, 2020 - frontiersin.org
… by a systemic impairment of bone mineral density (BMD). Genome-wide association studies
(GWAS) have identified hundreds of susceptibility loci for osteoporosis and BMD. However, …

[HTML][HTML] Twelve new genomic loci associated with bone mineral density

L Liu, M Zhao, ZG Xie, J Liu, HP Peng, YF Pei… - Frontiers in …, 2020 - frontiersin.org
association analysis of 2 genome-wide association study (… over 50 years old suffer osteoporotic
fracture in their remaining … osteoporosis is made from the measurement of bone mineral

A longitudinal genome-wide association study of bone mineral density mean and variability in the UK Biobank

D He, H Liu, W Wei, Y Zhao, Q Cai, S Shi, X Chu… - Osteoporosis …, 2023 - Springer
… Given the increasing number of genome-wide association studies (GWAS), … , osteoporosis,
and osteoporotic fractures, highlighting the importance of BMD as a determinant of fracture

[HTML][HTML] A genome-wide association study of bisphosphonate-associated atypical femoral fracture

M Kharazmi, K Michaëlsson, J Schilcher… - Calcified Tissue …, 2019 - Springer
… ) may affect bone mineral density and bone turnover following … a bisphosphonate for
osteoporosis prevention. Secondly, … were a mix of normal and osteoporotic women, and that only …

[HTML][HTML] Genome-wide polygenic risk score for major osteoporotic fractures in postmenopausal women using associated single nucleotide polymorphisms

Q Wu, J Jung - Journal of Translational Medicine, 2023 - Springer
… (SNPs), associated with osteoporosis, bone mineral density (BMD) and osteoporotic
from a recent genome-wide association study (GWAS) for bone mineral density estimated from …

A multiethnic whole genome sequencing study to identify novel loci for bone mineral density

J Greenbaum, KJ Su, X Zhang, Y Liu… - Human Molecular …, 2022 - academic.oup.com
… over the age of 50 will experience osteoporotic fractures in their remaining lifetime, and the
… for OSteoporosis (GEFOS) (5,6) and the UK Biobank (7). Genome-wide association studies (…

[HTML][HTML] GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

U Styrkarsdottir, OA Stefansson, K Gunnarsdottir… - Nature …, 2019 - nature.com
studied in large genome wide association (GWA) studies, … our criteria of genome-wide
significance 30 in the association analysis, … Osteoporotic fractures included low trauma fractures