… like a low dose of cytarabine or hypomethylating agents is … Anthracycline antibiotics
overcoming multidrug resistance … the extra function of PU.1 independent of GATA-1. Epigenetic …

… sette transporters and developing multidrug resistance inhibitors, are … patients often take
cytarabine (ara-C), a nucleoside-… The anthracycline-modified drugs annamycin and doxorubicin-…

… upon treatment with cytarabine- and anthracycline-based … Proteasome inhibitors like
bortezomib (velcade) and … its prosurvival functions through mechanisms that are independent of its …

… Multi-drug resistance (MDR) is a leading cause of cancer-… Further, many antineoplastic
compounds, including anthracyclines, … Resistance to cytarabine, 5-fluorouracil or oxaliplatin in …

… treatment with thiostrepton or bortezomib and TMZ restores … ) expression, a known culprit
in multidrug resistance [88]. … Cytarabine and anthracycline are the standard treatments for …

… induction and suppression of multidrug resistance gene 1/MDR1, … along with doxorubicin
(anthracycline antibiotic) induced … As expected bortezomib increased bortezomib triggered …

… inhibitors (topotecan) and anthracyclines. However, the … been found to cause multidrug
resistance in NB cells. Thus, … and induces cell cycle arrest, and also bortezomib treatment …

… and navitoclax potentiated the effect of bortezomib in the OPM-2 … or cytarabine with venetoclax
synergistically induced cell … of a MAPK-independent inhibition mechanism that could lead …

… CPZ can circumvent multi-drug resistance in cancer cells (91)… agents cytarabine, etoposide
and daunorubicin in vitro, and … of 99 patients with anthracycline-resistant metastatic breast …

… to the presence of multidrug resistance phenotype, which … resistance to tipifamib and
resistance to anthracyclines or … Tipifarnib and bortezomib are synergistic and overcome cell …