[HTML][HTML] Evaluation of the Efficacy of a Cholera Toxin-Based Staphylococcus aureus Vaccine against Bovine Intramammary Challenge

HA Alabdullah, E Overgaard, D Scarbrough… - Vaccines, 2020 - mdpi.com
aureus vaccination in cattle include whole-cell live and killed … doses this vaccine was found
to stimulate significant S. … aureus superantigens (SAgs) can activate specific T-cell subsets, …

[HTML][HTML] Symposium review: Features of Staphylococcus aureus mastitis pathogenesis that guide vaccine development strategies

J Côté-Gravel, F Malouin - Journal of dairy science, 2019 - Elsevier
… a diversity of superantigen arrays, each having the ability to induce Vβ-specific proliferation
of bovine T cells and with some arrays able to stimulate the entire T cell repertoire (Wilson et …

Exploring the Staphylococcus aureus cell wall for invariant immunodominant targets

YM Hernández - 2020 - research.rug.nl
… abundant T cells in the healthy mammary gland of cows have … aureus and that can act as
superantigens on host immune … is most frequently isolated from infected udders in dairy cattle 4. …

[HTML][HTML] … and immune characteristics in first-lactation Holstein-Friesian cows following intramammary infection with genotypically distinct Staphylococcus aureus …

DA Niedziela, MP Murphy, J Grant, OM Keane… - Journal of dairy …, 2020 - Elsevier
Staphylococcus aureus was recovered from milk of all … This is the first in vivo study in cattle
that confirms that 2 Staphstimulates production of cytokines and chemokines by the epithelial …

[HTML][HTML] Immunoproteomic analysis of the serum IgG response to cell wall-associated proteins of Staphylococcus aureus strains belonging to CC97 and CC151

SD Drumm, P Cormican, RA Owens, J Mitchell… - Veterinary …, 2023 - Springer
Staphylococcus aureus lineages associated with bovine … approach was used to identify the
repertoire of, and interrogate the … All cows in this group also had a reactive band at ~50 kDa. …

Staphylococcal surface proteins as vaccine candidates for the control of Staphylococcal mastitis in dairy cows

JJ Vidlund - 2022 - trace.tennessee.edu
… gland, is the single most costly disease of dairy cattle. … Although these staphylococcal
superantigens can work as a … helper T cells activate CD8+ T cells to became cytotoxic T cells that …

Staphylococcus aureus: setting its sights on the human innate immune system

KD Buchan, SJ Foster, SA Renshaw - Microbiology, 2019 - microbiologyresearch.org
… the staphylococcal superantigens, staphylococcal superantigen… PAMPs or inflammatory
signals, stimulating amplification of the … evidence of a human-to-cattle host jump shortly after their …

[HTML][HTML] Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies

…, S Rittenhouse, F Bagnoli, S Phogat - Frontiers in …, 2021 - frontiersin.org
cells appeared to stimulate antigen-specific cytokine production in donor-matched CD8 + T
cells to a greater degree than that of CD4 + T cells (57… SpA acts both as a B cell superantigen

[HTML][HTML] Comparative genomic analysis of Staphylococcus aureus isolates associated with either bovine intramammary infections or human infections demonstrates …

S Park, D Jung, B O'Brien, J Ruffini… - Microbial …, 2022 - microbiologyresearch.org
aureus bovine mastitis is a costly disease in dairy cattle. Despite its clinical importance and
overall burden … We identified a total of 103 virulence genes from 65 bovine IMI-associated S. …

[HTML][HTML] Comparative genomics of Staphylococcus aureus associated with subclinical and clinical bovine mastitis

LS Rocha, DM Silva, MP Silva, PMP Vidigal… - PLoS …, 2019 - journals.plos.org
bovine mastitis and is widely distributed in dairy cattle herds … repertoire of VF previously
described for bovine strains of S. … are considered superantigens due to their stimulation of T-cell