The HIV-1 latent reservoir is largely sensitive to circulating T cells
… of T cell escape, we mapped HIV-1-specific T cell responses … in vaccine immunogen: The
proportion of reactive T cell … -wide patterns of escape (ie escape in 32% of reactive T cell epito…
proportion of reactive T cell … -wide patterns of escape (ie escape in 32% of reactive T cell epito…
[HTML][HTML] Advances in HIV-1-specific chimeric antigen receptor cells to target the HIV-1 reservoir
MC Choudhary, JC Cyktor, SA Riddler - Journal of Virus Eradication, 2022 - Elsevier
… of the broadly neutralizing HIV-1 specific antibody VRC01 to … ” of CAR T cells with the timing
of administered HIV-1-specific … a new CAR T cell target and a nanoparticulate RNA vaccine …
of administered HIV-1-specific … a new CAR T cell target and a nanoparticulate RNA vaccine …
Immunologic control of HIV-1: what have we learned and can we induce it?
DC Rogan, M Connors - Current HIV/AIDS Reports, 2021 - Springer
… of an effective CD8 + T cell response by either vaccination or … This finding was corroborated
by genome-wide association … HIV-1-specific CD8 + T cells likely eliminates CD4 + T cells …
by genome-wide association … HIV-1-specific CD8 + T cells likely eliminates CD4 + T cells …
Viral T-cell epitopes–Identification, characterization and clinical application
… such as the TCR sequencing-based assays become broadly … Although HIV-1-specific T-cell
responses were demonstrated … of virus-specific T cells after vaccination requires some time …
responses were demonstrated … of virus-specific T cells after vaccination requires some time …
[HTML][HTML] New approaches to dendritic cell-based therapeutic vaccines against HIV-1 infection
M Espinar-Buitrago, MA Muñoz-Fernández - Frontiers in immunology, 2022 - frontiersin.org
… case, the expansion of the DCs was induced, but the CD8+ T … the CD4+ T cells and CD8+
T cells response and increased … a therapeutic vaccine is to induce strong and broad specific …
T cells response and increased … a therapeutic vaccine is to induce strong and broad specific …
Challenges and opportunities of using adoptive T-cell therapy as part of an HIV cure strategy
Y Zhou, CR Maldini, J Jadlowsky… - The Journal of Infectious …, 2021 - academic.oup.com
… cell product can be infused as a preventative vaccine or as … HIV-1-specific chimeric antigen
receptors based on broadly … Stimulation of HIV-1specific cytolytic T lymphocytes facilitates …
receptors based on broadly … Stimulation of HIV-1specific cytolytic T lymphocytes facilitates …
Immune checkpoint blockade in HIV
… ART will likely require potent T cell function, but chronic HIV … , latency-reversing agents or
vaccines, by identifying pathways … the expansion capacity of HIV-specific CD8+T-cells. However…
vaccines, by identifying pathways … the expansion capacity of HIV-specific CD8+T-cells. However…
[PDF][PDF] Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells
M Dube, O Tastet, C Dufour, G Sannier, N Brassard… - Cell Host & Microbe, 2023 - cell.com
… We used a T cell receptor (TCR)-dependent activation… + and CD8+ T cell responses, indicating
a broader relationship than … + and CD8+ T cell responses in a chronic state of expansion, …
a broader relationship than … + and CD8+ T cell responses in a chronic state of expansion, …
Conserved multiepitope vaccine constructs: A potent HIV-1 therapeutic vaccine in clinical trials
E Akbari, M Seyedinkhorasani… - Brazilian Journal of …, 2023 - SciELO Brasil
… It can induce effective HIV-1-specific immunity to control … regions containing a wide range of
critical T- and B-cell epitopes of … HIV-1-specific T cell responses. J Transl Med. 2011;9:1-20.- …
critical T- and B-cell epitopes of … HIV-1-specific T cell responses. J Transl Med. 2011;9:1-20.- …
[HTML][HTML] Generating and measuring effective vaccine-elicited HIV-specific CD8+ T cell responses
GM Borgo, RL Rutishauser - Current Opinion in HIV and AIDS, 2023 - journals.lww.com
… functional and phenotypic features of HIV-specific CD8 + T … HIV cannot control viremia without
antiretroviral therapy (ART). Rare … the vaccine did not generally elicit a broad CD8 + T cell …
antiretroviral therapy (ART). Rare … the vaccine did not generally elicit a broad CD8 + T cell …