Fungal pathogens: shape-shifting invaders

K Min, AM Neiman, JB Konopka - Trends in microbiology, 2020 - cell.com
… Cell morphology also impacts how fungi interact with the immune system [ … capsulatum to
replicate safely within the phagosomes of macrophages without further attack by the immune …

Integrity under stress: Host membrane remodelling and damage by fungal pathogens

J Westman, B Hube, GD Fairn - Cellular microbiology, 2019 - Wiley Online Library
… fumigatus hyphae are capable of manipulating epithelial cells by … within a phagosome, the
fungus escapes the phagosome and … Following escape from the macrophage, C. albicans …

The Nature of the Fungal Cargo Induces Significantly Different Temporal Programmes of Macrophage Phagocytosis

NAR Gow, MF Alonso, JM Bain, FM Rudkin… - Available at SSRN … - papers.ssrn.com
evasion mechanisms. Therefore, simultaneous assessment … differences in the rates of
engulfment and phagosome 106 … instrumental in determining the outcomes of interactions with …

In vitro infection models to study fungal–host interactions

A Last, M Maurer, A S. Mosig… - FEMS Microbiology …, 2021 - academic.oup.com
… These ex vivo models offer the advantage that conditions can be easily manipulated and are
… fungal cells to evade macrophage phagocytosis or to escape from phagosomes. Masking of …

[HTML][HTML] Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection

TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
… Thus, spores can evade host immunity much more efficiently than yeast cells, … phagosome
may lead to the formation of titanized cryptococcal cells with consequential macrophage

[HTML][HTML] Mucorales species and macrophages

…, E Navarro, MI Navarro-Mendoza, C Pérez-Arques… - Journal of Fungi, 2020 - mdpi.com
phagosomal maturation and species-specific mechanisms to either survive as dormant spores
inside the macrophage, as Rhizopus species, or geminate and escape, … manipulation. The …

How environmental fungi cause a range of clinical outcomes in susceptible hosts

ST Denham, MA Wambaugh, JCS Brown - Journal of molecular biology, 2019 - Elsevier
… We discuss immune evasion strategies during early infection, from disruption of host immune
cells to major changes in fungal cell … granulocyte-macrophage colony-stimulating factor …

Cryptococcal pathogenicity and morphogenesis

HC De Oliveira, N Trevijano-Contador… - Current Fungal Infection …, 2019 - Springer
… paying special attention to its unique morphological program during interaction with hosts. …
If macrophage attack is evaded, Cryptococcus is able to proliferate within the phagosome

Vomocytosis: what we know so far

PI Seoane, RC May - Cellular microbiology, 2020 - Wiley Online Library
… were seen to be recruited to Cryptococcus-containing phagosomes. Of these, autophagy-…
infection of macrophages with C. neoformans, but rather a much more widely used escape/…

[HTML][HTML] Talaromyces marneffei Infection: Virulence, Intracellular Lifestyle and Host Defense Mechanisms

K Pruksaphon, JD Nosanchuk, K Ratanabanangkoon… - Journal of Fungi, 2022 - mdpi.com
… knowledge regarding the dynamic interaction between T. … pathogen for manipulating and
evading host immune cells. … macrophages to survive and replicate inside the phagosome, …